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CATH Superfamily 3.40.50.720

NAD(P)-binding Rossmann-like Domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 291312: Oxidoreductase, NAD-binding domain protein

There are 5 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
L-arabinose 1-dehydrogenase. [EC: 1.1.1.46]
L-arabinose + NAD(+) = L-arabinono-1,4-lactone + NADH.
    		 210 A0A026UFT5 A0A026UFT5 A0A027TZL9 A0A027TZL9 A0A028AJH6 A0A028AJH6 A0A028EBC4 A0A028EBC4 A0A029PKU3 A0A029PKU3
    (200 more...)
    Scyllo-inositol 2-dehydrogenase (NADP(+)). [EC: 1.1.1.371]
    Scyllo-inositol + NADP(+) = 2,4,6/3,5-pentahydroxycyclohexanone + NADPH.
    • The enzyme, found in the bacterium Bacillus subtilis, has no activity with NAD(+) (cf. EC 1.1.1.370).
    		 18 A0A0J1FQN8 A0A0J1FQN8 A0A162QN61 A0A162QN61 A0A1A0CD34 A0A1A0CD34 A0A1A5VSR3 A0A1A5VSR3 A0A1A7BZ79 A0A1A7BZ79
    (8 more...)
    D-galactose 1-dehydrogenase. [EC: 1.1.1.48]
    D-galactose + NAD(+) = D-galactono-1,4-lactone + NADH.
    • This enzyme is part of the De Ley-Doudoroff pathway, which is used by some bacteria during growth on D-galactose.
    		 4 A0A085U7I6 A0A085U7I6 E0SBZ2 E0SBZ2
    Inositol 2-dehydrogenase. [EC: 1.1.1.18]
    Myo-inositol + NAD(+) = 2,4,6/3,5-pentahydroxycyclohexanone + NADH.
      		 4 Q39KT7 Q39KT7 S2DC95 S2DC95
      Precorrin-2 C(20)-methyltransferase. [EC: 2.1.1.130]
      S-adenosyl-L-methionine + precorrin-2 = S-adenosyl-L-homocysteine + precorrin-3A.
        		 2 U2EDN3 U2EDN3