The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 291142: Putative 2-hydroxyacid dehydrogenase UNK4.10

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Glyoxylate reductase. [EC: 1.1.1.26]
Glycolate + NAD(+) = glyoxylate + NADH.
  • Reduces glyoxylate to glycolate or hydroxypyruvate to D-glycerate.
9 A0A0L8VJ46 B3LPB3 B5VQE0 C7GP89 C8ZGP8 E7KHC8 E7KT90 H0GM60 P53839
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