The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"NAD(P)-binding Rossmann-like Domain
".
FunFam 291122: Malate dehydrogenase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
L-malate dehydrogenase activity GO:0030060
Catalysis of the reaction: (S)-malate + NAD+ = oxaloacetate + NADH + H+.
|
1 | P22133 (/IDA) |
|
L-malate dehydrogenase activity GO:0030060
Catalysis of the reaction: (S)-malate + NAD+ = oxaloacetate + NADH + H+.
|
1 | P22133 (/IMP) |
There are 4 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Gluconeogenesis GO:0006094
The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
|
1 | P22133 (/IEP) |
|
Gluconeogenesis GO:0006094
The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
|
1 | P22133 (/IMP) |
|
Malate metabolic process GO:0006108
The chemical reactions and pathways involving malate, the anion of hydroxybutanedioic acid, a chiral hydroxydicarboxylic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle.
|
1 | P22133 (/TAS) |
|
Protein import into peroxisome matrix GO:0016558
The import of proteins into the peroxisomal matrix. A peroxisome targeting signal (PTS) binds to a soluble receptor protein in the cytosol, and the resulting complex then binds to a receptor protein in the peroxisome membrane and is imported. The cargo protein is then released into the peroxisome matrix.
|
1 | P22133 (/IMP) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | P22133 (/IDA) |
|
Nuclear periphery GO:0034399
The portion of the nuclear lumen proximal to the inner nuclear membrane.
|
1 | P22133 (/IDA) |