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CATH Superfamily 3.40.50.720

NAD(P)-binding Rossmann-like Domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 289832: Prephenate dehydrogenase

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Prephenate dehydrogenase. [EC: 1.3.1.12]
Prephenate + NAD(+) = 4-hydroxyphenylpyruvate + CO(2) + NADH.
  • This enzyme in the enteric bacteria also possesses EC 5.4.99.5 activity and converts chorismate into prephenate.
 157 A0A068ECA7 A0A069F572 A0A069FTV6 A0A077VB35 A0A080UJ78 A0A085UHT6 A0A0A7T1A0 A0A0E0VNP7 A0A0E1AI04 A0A0E1VHN9
(147 more...)
Arogenate dehydrogenase. [EC: 1.3.1.43]
L-arogenate + NAD(+) = L-tyrosine + NADH + CO(2).
  • Arogenate dehydrogenases may utilize NAD(+) (EC 1.3.1.43), NADP(+) (EC 1.3.1.78), or both (EC 1.3.1.79).
  • NAD(+)-specific enzymes have been reported from some bacteria and plants.
  • Some enzymes also possess the activity of EC 1.3.1.12.
 105 A0A077UMK8 A0A077VB35 A0A0D1JPD9 A0A0E0VNP7 A0A0E1AI04 A0A0E1VHN9 A0A0E1XG53 A0A0G7GX70 A0A0H3K7Z2 A0A0K6M1I1
(95 more...)
Prephenate dehydrogenase (NADP(+)). [EC: 1.3.1.13]
Prephenate + NADP(+) = 4-hydroxyphenylpyruvate + CO(2) + NADPH.
    		 1 M5QXY4