The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 289787: Potassium channel subfamily T member 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Calcium-activated potassium channel activity GO:0015269
Enables the calcium concentration-regulatable energy-independent passage of potassium ions across a lipid bilayer down a concentration gradient.
17 A0A0B4JD38 (/ISS) A0A0B4K738 (/ISS) A0A0B4KEJ9 (/ISS) A0A0B4KEQ3 (/ISS) A0A0B4KF87 (/ISS) A0A0B4KFK3 (/ISS) A0A0C4DHC4 (/ISS) A8DY93 (/ISS) A8DY94 (/ISS) B2MZB8 (/ISS)
(7 more)
Intracellular sodium activated potassium channel activity GO:0005228
Enables the transmembrane transfer of potassium by a channel that opens in response to stimulus by a sodium ion or ions. Transport by a channel involves facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism. Sodium activated potassium channels have distinctive properties, including a large single channel conductance, subconductance states, and a block of single channel currents at positive potentials, similar to inward rectification.
9 A0A0B4JD38 (/IDA) A0A0B4K738 (/IDA) A0A0B4KEJ9 (/IDA) A0A0B4KEQ3 (/IDA) A0A0B4KF87 (/IDA) A0A0B4KFK3 (/IDA) A0A0C4DHC4 (/IDA) A8DY93 (/IDA) A8DY94 (/IDA)
Calcium-activated potassium channel activity GO:0015269
Enables the calcium concentration-regulatable energy-independent passage of potassium ions across a lipid bilayer down a concentration gradient.
8 B2MZB8 (/IDA) G5ECD1 (/IDA) G5EDJ1 (/IDA) H9G2R3 (/IDA) H9G2R4 (/IDA) H9G2R6 (/IDA) H9G2R7 (/IDA) Q565B7 (/IDA)
Outward rectifier potassium channel activity GO:0015271
Enables the transmembrane transfer of a potassium ion by an outwardly-rectifying voltage-gated channel. An outwardly rectifying current-voltage relation is one where at any given driving force the outward flow of K+ ions exceeds the inward flow for the opposite driving force.
8 B2MZB8 (/IDA) G5ECD1 (/IDA) G5EDJ1 (/IDA) H9G2R3 (/IDA) H9G2R4 (/IDA) H9G2R6 (/IDA) H9G2R7 (/IDA) Q565B7 (/IDA)
Intracellular sodium activated potassium channel activity GO:0005228
Enables the transmembrane transfer of potassium by a channel that opens in response to stimulus by a sodium ion or ions. Transport by a channel involves facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism. Sodium activated potassium channels have distinctive properties, including a large single channel conductance, subconductance states, and a block of single channel currents at positive potentials, similar to inward rectification.
1 Q6UVM4 (/TAS)
Potassium channel activity GO:0005267
Enables the facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
1 Q9Z258 (/IDA)
Potassium channel activity GO:0005267
Enables the facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
1 D3Z649 (/ISO)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
1 Q6UVM4 (/TAS)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Potassium ion transport GO:0006813
The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
9 B2MZB8 (/IDA) G5ECD1 (/IDA) G5EDJ1 (/IDA) H9G2R3 (/IDA) H9G2R4 (/IDA) H9G2R6 (/IDA) H9G2R7 (/IDA) Q565B7 (/IDA) Q9Z258 (/IDA)
Potassium ion transport GO:0006813
The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
9 A0A0B4JD38 (/ISS) A0A0B4K738 (/ISS) A0A0B4KEJ9 (/ISS) A0A0B4KEQ3 (/ISS) A0A0B4KF87 (/ISS) A0A0B4KFK3 (/ISS) A0A0C4DHC4 (/ISS) A8DY93 (/ISS) A8DY94 (/ISS)
Neuron projection morphogenesis GO:0048812
The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites.
9 A0A0B4JD38 (/IMP) A0A0B4K738 (/IMP) A0A0B4KEJ9 (/IMP) A0A0B4KEQ3 (/IMP) A0A0B4KF87 (/IMP) A0A0B4KFK3 (/IMP) A0A0C4DHC4 (/IMP) A8DY93 (/IMP) A8DY94 (/IMP)
Potassium ion transmembrane transport GO:0071805
A process in which a potassium ion is transported from one side of a membrane to the other.
9 A0A0B4JD38 (/IDA) A0A0B4K738 (/IDA) A0A0B4KEJ9 (/IDA) A0A0B4KEQ3 (/IDA) A0A0B4KF87 (/IDA) A0A0B4KFK3 (/IDA) A0A0C4DHC4 (/IDA) A8DY93 (/IDA) A8DY94 (/IDA)
Positive regulation of neurotransmitter secretion GO:0001956
Any process that activates or increases the frequency, rate or extent of the regulated release of a neurotransmitter.
1 H9G2R4 (/IMP)
Potassium ion transport GO:0006813
The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 D3Z649 (/ISO)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
9 A0A0B4JD38 (/ISS) A0A0B4K738 (/ISS) A0A0B4KEJ9 (/ISS) A0A0B4KEQ3 (/ISS) A0A0B4KF87 (/ISS) A0A0B4KFK3 (/ISS) A0A0C4DHC4 (/ISS) A8DY93 (/ISS) A8DY94 (/ISS)
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
8 B2MZB8 (/IDA) G5ECD1 (/IDA) G5EDJ1 (/IDA) H9G2R3 (/IDA) H9G2R4 (/IDA) H9G2R6 (/IDA) H9G2R7 (/IDA) Q565B7 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 D3Z649 (/ISO)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q9Z258 (/IDA)