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CATH Superfamily 3.40.50.720

NAD(P)-binding Rossmann-like Domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 289013: Potassium uptake protein KtrA

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Adenosylhomocysteinase. [EC: 3.3.1.1]
S-adenosyl-L-homocysteine + H(2)O = L-homocysteine + adenosine.
  • The NAD(+) cofactor appears to bring about a transient oxidation at C-3' of the 5'-deoxyadenosine residue, thus labilizing the thioether bond cf. EC 5.5.1.4.
 244 A0A023PA19 A0A023PA19 A0A063CRP4 A0A063CRP4 A0A0B5NRR7 A0A0B5NRR7 A0A0B5QQT6 A0A0B5QQT6 A0A0D0HUT5 A0A0D0HUT5
(234 more...)
Leucine dehydrogenase. [EC: 1.4.1.9]
L-leucine + H(2)O + NAD(+) = 4-methyl-2-oxopentanoate + NH(3) + NADH.
  • Also acts on isoleucine, valine, norvaline and norleucine.
 12 A0A1L8SG51 A0A1L8SG51 C9A4I4 C9A4I4 F0EN98 F0EN98 J0XLR7 J0XLR7 S4B6Y4 S4B6Y4
(2 more...)
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