The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"NAD(P)-binding Rossmann-like Domain
".
FunFam 288578: Polyketide synthase type I
There are 6 EC terms in this cluster
Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
EC Term | Annotations | Evidence |
---|---|---|
Beta-ketoacyl-[acyl-carrier-protein] synthase I.
[EC: 2.3.1.41]
Acyl-[acyl-carrier-protein] + malonyl-[acyl-carrier-protein] = 3-oxoacyl- [acyl-carrier-protein] + CO(2) + [acyl-carrier-protein].
|
108 |
A0A0E7SSY2
A0A0E8W3N5
A0A0H3L915
A0A0H3M8C2
A0A0J6W364
A0A0K2HWN8
A0A0T7LGB0
A0A0T7LHF4
A0A0T7LKK8
A0A0T7LQY9 (98 more...) |
6-deoxyerythronolide-B synthase.
[EC: 2.3.1.94]
Propanoyl-CoA + 6 (2S)-methylmalonyl-CoA + 6 NADPH = 6-deoxyerythronolide B + 7 CoA + 6 CO(2) + H(2)O + 6 NADP(+).
|
19 |
A0A0E2WPM4
A0A0E2WXI9
A0A0E2WXI9
A0A0H2ZR47
A0A0H2ZTV9
A0A0H2ZTV9
A0A0N1GK83
A0A0N1H250
A0A100JUB7
D5P328 (9 more...) |
[Acyl-carrier-protein] S-malonyltransferase.
[EC: 2.3.1.39]
Malonyl-CoA + an [acyl-carrier-protein] = CoA + a malonyl-[acyl-carrier- protein].
|
16 |
A0A0K3BQV0
A0A1L7MIS0
A0A1L7MIS0
L1KT20
M9U189
N1M2X5
S5TL42
W7IUF2
W7J4H9
W7J4T6 (6 more...) |
Mycocerosate synthase.
[EC: 2.3.1.111]
(1) A long-chain acyl-CoA + 3 methylmalonyl-CoA + 6 NADPH + a holo- [mycocerosate synthase] = a trimethylated-mycocerosoyl-[mycocerosate synthase] + 4 CoA + 3 CO(2) + 6 NADP(+) + 3 H(2)O. (2) A long-chain acyl-CoA + 4 methylmalonyl-CoA + 8 NADPH + a holo- [mycocerosate synthase] synthase = a tetramethylated-mycocerosoyl- [mycocerosate synthase] + 5 CoA + 4 CO(2) + 8 NADP(+) + 4 H(2)O.
|
5 | A0A0N1H250 G0PRM2 G0PRM4 G0PUE2 G0Q9T9 |
NADPH:quinone reductase.
[EC: 1.6.5.5]
NADPH + 2 quinone = NADP(+) + 2 semiquinone.
|
3 | G0PRM5 G0Q9U2 G7LSJ3 |
6-methylsalicylic acid synthase.
[EC: 2.3.1.165]
Acetyl-CoA + 3 malonyl-CoA + NADPH = 6-methylsalicylate + 4 CoA + 3 CO(2) + NADP(+).
|
2 | A0A0N1GK83 N0CTQ6 |