The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 287574: Bifunctional protein FolD

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Methylenetetrahydrofolate dehydrogenase (NADP(+)). [EC: 1.5.1.5]
5,10-methylenetetrahydrofolate + NADP(+) = 5,10- methenyltetrahydrofolate + NADPH.
    236 A0A068E604 A0A069F4R6 A0A069FS76 A0A077UIG0 A0A077VDN9 A0A085UF77 A0A0A8HS87 A0A0D0RLP4 A0A0D1JMN8 A0A0D6XNN1
    (226 more...)
    Methenyltetrahydrofolate cyclohydrolase. [EC: 3.5.4.9]
    5,10-methenyltetrahydrofolate + H(2)O = 10-formyltetrahydrofolate.
      235 A0A068E604 A0A069F4R6 A0A069FS76 A0A077UIG0 A0A077VDN9 A0A085UF77 A0A0A8HS87 A0A0D0RLP4 A0A0D1JMN8 A0A0D6XNN1
      (225 more...)
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