The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 286379: Shikimate 5-dehydrogenase

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
3-dehydroquinate dehydratase. [EC: 4.2.1.10]
3-dehydroquinate = 3-dehydroshikimate + H(2)O.
    7 A0A070A1P7 A0A0E9CYE0 A0A0E9D6U7 A0A0E9DMU1 A0A0H3ML24 O84375 P56961
    Shikimate dehydrogenase. [EC: 1.1.1.25]
    Shikimate + NADP(+) = 3-dehydroshikimate + NADPH.
    • NAD(+) cannot replace NADP(+).
    • In higher organisms, this enzyme forms part of a multienzyme complex with EC 4.2.1.10.
    6 A0A070A1P7 A0A0E9D6U7 A0A0H2X124 A0A1J0NM14 O84375 P56961