The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 286280: Alcohol dehydrogenase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Alcohol dehydrogenase (NAD) activity GO:0004022
Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+.
25 B4M8Y0 (/ISS) P07162 (/ISS) P21518 (/ISS) P21898 (/ISS) P22245 (/ISS) P23236 (/ISS) P23237 (/ISS) P25139 (/ISS) P25720 (/ISS) P27581 (/ISS)
(15 more)
Alcohol dehydrogenase (NAD) activity GO:0004022
Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+.
1 P00334 (/IDA)
Alcohol dehydrogenase (NAD) activity GO:0004022
Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+.
1 P00334 (/IMP)
Acetaldehyde dehydrogenase (acetylating) activity GO:0008774
Catalysis of the reaction: acetaldehyde + CoA + NAD+ = acetyl-CoA + NADH + H+.
1 P00334 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 P00334 (/IPI)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Alcohol catabolic process GO:0046164
The chemical reactions and pathways resulting in the breakdown of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.
5 B4M8Y0 (/ISS) Q50L96 (/ISS) Q9NG40 (/ISS) Q9NG42 (/ISS) Q9U8S9 (/ISS)
Alcohol metabolic process GO:0006066
The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.
1 P00334 (/IDA)
Ethanol metabolic process GO:0006067
The chemical reactions and pathways involving ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation.
1 P00334 (/IMP)
Ethanol oxidation GO:0006069
An ethanol metabolic process in which ethanol is converted to acetyl-CoA via acetaldehyde and acetate.
1 P00334 (/IDA)
Acetaldehyde metabolic process GO:0006117
The chemical reactions and pathways involving acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol.
1 P00334 (/IDA)
Acetaldehyde metabolic process GO:0006117
The chemical reactions and pathways involving acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol.
1 P00334 (/IMP)
Alcohol catabolic process GO:0046164
The chemical reactions and pathways resulting in the breakdown of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.
1 P00334 (/IMP)
Behavioral response to ethanol GO:0048149
Any process that results in a change in the behavior of an organism as a result of an ethanol stimulus.
1 P00334 (/IMP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 P00334 (/IDA)
Protein complex GO:0043234
A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
1 P00334 (/IPI)