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CATH Superfamily 3.40.50.720

NAD(P)-binding Rossmann-like Domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 242894: Bifunctional glyoxylate/hydroxypyruvate reductase ...

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Glyoxylate reductase (NADP(+)). [EC: 1.1.1.79]
Glycolate + NADP(+) = glyoxylate + NADPH.
  • Also reduces hydroxypyruvate to glycerate.
  • Has some affinity for NAD(+).
 11 A0A083UDX2 A0A0C1ZVH9 A0A0C2A3M2 A0A0E1E4X5 A0A0K1QM73 A0A1H1PDL0 A0A1K1YGW3 A0A1K1ZQ31 J2EW09 Q4KI01
(1 more...)
Hydroxypyruvate reductase. [EC: 1.1.1.81]
D-glycerate + NAD(P)(+) = hydroxypyruvate + NAD(P)H.
    		 7 A0A083UDX2 A0A0C1ZVH9 A0A0C2A3M2 A0A0E1E4X5 A0A0K1QM73 A0A1H1PDL0 S2FLV6
    Gluconate 2-dehydrogenase. [EC: 1.1.1.215]
    D-gluconate + NADP(+) = 2-dehydro-D-gluconate + NADPH.
    • Also acts on L-idonate, D-galactonate and D-xylonate.
    		 4 K9NFQ3 Q3KHS7 W6UVC9 W6VIR3