The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
HUPs
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 87579: tRNA(Ile)-lysidine synthase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
TRNA(Ile)-lysidine synthetase. [EC: 6.3.4.19]
(tRNA(Ile2))-cytidine(34) + L-lysine + ATP = (tRNA(Ile2))-lysidine(34) + AMP + diphosphate + H(2)O.
  • The bacterial enzyme modifies the wobble base of the CAU anticodon of tRNA(Ile) at the oxo group in position 2 of cytidine(34).
  • This modification determines both codon and amino acid specificities of tRNA(Ile).
1033 A0A010YGJ2 A0A011U2P0 A0A014M5A1 A0A022L1T8 A0A022LEI7 A0A022LS10 A0A024H6Z5 A0A024K6L9 A0A024M502 A0A024QY46
(1023 more...)