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CATH Superfamily 3.40.50.620

HUPs

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
HUPs
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 86600: Valine--tRNA ligase, mitochondrial

There are 5 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Valine--tRNA ligase. [EC: 6.1.1.9]
ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val).
    		 713 A0A017H9M6 A0A017HQT3 A0A023DXM9 A0A037UX42 A0A037ZJD0 A0A037ZJD0 A0A058ZJ19 A0A059IR42 A0A060NHK5 A0A060NMU7
    (703 more...)
    Leucine--tRNA ligase. [EC: 6.1.1.4]
    ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu).
      		 181 A0A022L8S4 A0A031FZG7 A0A061LWM3 A0A091C9B5 A0A0B1XV48 A0A0B2BB70 A0A0D0IKB7 A0A0G0IK79 A0A0G0NB86 A0A0G0PV73
      (171 more...)
      Isoleucine--tRNA ligase. [EC: 6.1.1.5]
      ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl- tRNA(Ile).
        		 40 A0A060RW55 A0A075FS45 A0A075FT77 A0A077TTA0 A0A077XK71 A0A077YBB8 A0A078KFT8 A0A086PGF8 A0A086PPD8 A0A0G0LHG7
        (30 more...)
        Methionine--tRNA ligase. [EC: 6.1.1.10]
        ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl- tRNA(Met).
        • In those organisms producing N-formylmethionyl-tRNA(fMet) for translation initiation, this enzyme also recognizes the initiator tRNA(fMet) and catalyzes the formation of L-methionyl-tRNA(fMet), the substrate for EC 2.1.2.9.
        		 4 A0A0G0LLB7 A0A0G1S6K7 A0A0G4B0J4 A0A142XMP5
        Carboxylesterase. [EC: 3.1.1.1]
        A carboxylic ester + H(2)O = an alcohol + a carboxylate.
        • Wide specificity; also hydrolyzes vitamin A esters.
        • The enzymes from microsomes also catalyze the reactions of EC 3.1.1.2, EC 3.1.1.5, EC 3.1.1.6, EC 3.1.1.23, EC 3.1.1.28, EC 3.1.2.2, EC 3.5.1.4, and EC 3.5.1.13.
        • Formerly EC 3.1.1.12.
        		 1 A0A170XKD0