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CATH Superfamily 3.40.50.360

Flavodoxin domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 7950: NADH-dependent FMN reductase MsuE

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
FMN reductase (NADPH). [EC: 1.5.1.38]
FMNH(2) + NADP(+) = FMN + NADPH.
  • The enzymes from bioluminescent bacteria contain FMN, while the enzyme from Escherichia coli does not.
  • The enzyme often forms a two-component system with monooxygenases such as luciferase.
  • Unlike EC 1.5.1.39, this enzyme does not use NADH as acceptor.
  • While FMN is the preferred substrate, the enzyme can also use FAD and riboflavin with lower activity.
  • Formerly EC 1.5.1.29 and EC 1.6.8.1.
 15 A0A073A0Y3 A0A0A8RNF9 A0A0E1AXF8 A0A0H2ZBC8 A0A0H3R518 A0A0P1DBJ1 A0A157WQE6 A0A1C7BL29 A0A1D5C1F6 A0A1E9CP62
(5 more...)
FAD reductase (NAD(P)H). [EC: 1.5.1.45]
FADH(2) + NAD(P)(+) = FAD + NAD(P)H.
  • This enzyme, isolated from the bacterium Geobacillus thermodenitrificans, participates in the pathway of tryptophan degradation.
  • The enzyme is part of a system that also includes a bifunctional riboflavin kinase/FMN adenylyltransferase and EC 1.14.14.8.
  • It can reduce either FAD or flavin mononucleotide (FMN) but prefers FAD.
  • The enzyme has a slight preference for NADPH as acceptor.
  • Cf. EC 1.5.1.37.
 14 A0A073A0Y3 A0A0E1AXF8 A0A0H2ZBC8 A0A0H3R518 A0A0P1DBJ1 A0A157WQE6 A0A1C7BL29 A0A1D5C1F6 A0A1E9CP62 A0A1F0I5X4
(4 more...)
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