View in Gene3D

CATH Superfamily 3.40.50.360

Flavodoxin domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 7183: NAD(P)H-dependent FMN reductase

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
FMN reductase (NADPH). [EC: 1.5.1.38]
FMNH(2) + NADP(+) = FMN + NADPH.
  • The enzymes from bioluminescent bacteria contain FMN, while the enzyme from Escherichia coli does not.
  • The enzyme often forms a two-component system with monooxygenases such as luciferase.
  • Unlike EC 1.5.1.39, this enzyme does not use NADH as acceptor.
  • While FMN is the preferred substrate, the enzyme can also use FAD and riboflavin with lower activity.
  • Formerly EC 1.5.1.29 and EC 1.6.8.1.
 298 A0A026RST8 A0A026RST8 A0A026UK94 A0A026UK94 A0A027U7C8 A0A027U7C8 A0A027ZK39 A0A027ZK39 A0A028E8N2 A0A028E8N2
(288 more...)
Transferred entry: 1.5.1.38, 1.5.1.39 and 1.5.1.41. [EC: 1.5.1.29]
    		102 A0A026RST8 A0A026RST8 A0A029I6X1 A0A029I6X1 A0A029IY40 A0A029IY40 A0A073FZX3 A0A073FZX3 A0A073GIC5 A0A073GIC5
    (92 more...)
    FMN reductase (NAD(P)H). [EC: 1.5.1.39]
    FMNH(2) + NAD(P)(+) = FMN + NAD(P)H.
    • The enzyme can utilize NADH and NADPH with similar reaction rates.
    • Different from EC 1.5.1.42 and EC 1.5.1.38.
    • The luminescent bacterium Vibrio harveyi possesses all three enzymes, while the bacterium Aliivibrio fischeri contains only this non- specific type.
    • Also reduces riboflavin and FAD, but more slowly.
    • Formerly EC 1.5.1.29 and EC 1.6.8.1.
    		 30 A0A073FZX3 A0A073FZX3 A0A073GIC5 A0A073GIC5 A0A074I865 A0A074I865 A0A080G217 A0A080G217 A0A0A0FAH7 A0A0A0FAH7
    (20 more...)