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CATH Superfamily 3.40.50.360

Flavodoxin domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 16153: NAD(P)H dehydrogenase [quinone] 1

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
NAD(P)H dehydrogenase (quinone). [EC: 1.6.5.2]
NAD(P)H + a quinone = NAD(P)(+) + a hydroquinone.
  • The enzyme catalyzes a two-electron reduction and has a preference for short-chain acceptor quinones, such as ubiquinone, benzoquinone, juglone and duroquinone.
  • The animal, but not the plant, form of the enzyme is inhibited by dicoumarol.
  • Formerly EC 1.6.99.2.
 16 A0A0C7APE1 A0A0H2ZIA3 A0A0P1DII4 A0A157VCC9 A0A1D5BT29 A0A1E9C673 A0A1F0I756 A0A1G5JVT6 G3QL89 P05982
(6 more...)
Ribosyldihydronicotinamide dehydrogenase (quinone). [EC: 1.10.5.1]
1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide + a quinone = 1-(beta-D- ribofuranosyl)nicotinamide + a quinol.
  • Unlike EC 1.6.5.2, this quinone reductase cannot use NADH or NADPH; instead it uses N-ribosyl- and N-alkyldihydronicotinamides.
  • Polycyclic aromatic hydrocarbons, such as benz[a]anthracene, and the estrogens 17-beta-estradiol and diethylstilbestrol are potent inhibitors, but dicoumarol is only a very weak inhibitor.
  • This enzyme can catalyze both 2-electron and 4-electron reductions, but one-electron acceptors, such as potassium ferricyanide, cannot be reduced.
  • Formerly EC 1.10.99.2.
 4 P16083 Q5RBB9 Q6AY80 Q9JI75
Transferred entry: 1.10.5.1. [EC: 1.10.99.2]
    		2 A0A0V3SA99 A6VD92