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CATH Superfamily 3.40.50.300

P-loop containing nucleotide triphosphate hydrolases

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 80000: ABC transporter, ATP-binding protein

There are 6 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Heme-transporting ATPase. [EC: 3.6.3.41]
ATP + H(2)O + heme(In) = ADP + phosphate + heme(Out).
  • An enzyme found in Gram-negative bacteria that exports heme.
 122 A0A017IJE5 A0A023YU34 A0A025C8W7 A0A026V4K1 A0A027U6Z5 A0A028AV17 A0A028E7W8 A0A029I990 A0A029IXS5 A0A029L0L9
(112 more...)
Adenosinetriphosphatase. [EC: 3.6.1.3]
ATP + H(2)O = ADP + phosphate.
  • Many enzymes previously listed under this number are now listed separately as EC 3.6.1.32 to EC 3.6.1.39.
  • The remaining enzymes, not separately listed on the basis of some function coupled with hydrolyzes of ATP, include enzymes dependent on Ca(2+), Mg(2+), anions, H(+) or DNA.
  • Formerly EC 3.6.1.4.
 21 A0A084ZX04 A0A085GGG0 A0A085GRT7 A0A085H407 A0A085HFZ2 A0A085IH71 A0A085U4E9 A0A0N0Z994 A0A198FHB8 A0A198GN72
(11 more...)
Nucleoside-triphosphate phosphatase. [EC: 3.6.1.15]
NTP + H(2)O = NDP + phosphate.
  • The enzyme is found in eukaryotes and thermophilic bacteria, but appears to be absent from mesophilic bacteria.
  • Also hydrolyzes nucleoside diphosphates, thiamine diphosphate and FAD.
  • The enzyme from the plant Pisum sativum (garden pea) is regulated by calmodulin.
 19 A0A084ZX04 A0A085GGG0 A0A085GRT7 A0A085H407 A0A085HFZ2 A0A085IH71 A0A0N0Z994 A0A198FHB8 A0A198GN72 A0A1B7HSA2
(9 more...)
Dethiobiotin synthase. [EC: 6.3.3.3]
ATP + 7,8-diaminononanoate + CO(2) = ADP + phosphate + dethiobiotin.
  • CTP has half the activity of ATP.
 2 C8T166 F5RTW1
Phosphonate-transporting ATPase. [EC: 3.6.3.28]
ATP + H(2)O + phosphonate(Out) = ADP + phosphate + phosphonate(In).
  • A bacterial enzyme that imports phosphonate and organophosphate anions.
 1 V3TZP8
Sulfate-transporting ATPase. [EC: 3.6.3.25]
ATP + H(2)O + sulfate(Out) = ADP + phosphate + sulfate(In).
  • A bacterial enzyme that imports sulfate and thiosulfate anions.
 1 V3TZP8