The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 627133: ABC transporter ATPase component

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Heme-transporting ATPase. [EC: 3.6.3.41]
ATP + H(2)O + heme(In) = ADP + phosphate + heme(Out).
  • An enzyme found in Gram-negative bacteria that exports heme.
140 A0A017IG48 A0A026RSU4 A0A026UI25 A0A029I6X5 A0A029IY44 A0A029KZ35 A0A029LSD5 A0A029PQ40 A0A061YMQ1 A0A062YF88
(130 more...)
Adenosinetriphosphatase. [EC: 3.6.1.3]
ATP + H(2)O = ADP + phosphate.
  • Many enzymes previously listed under this number are now listed separately as EC 3.6.1.32 to EC 3.6.1.39.
  • The remaining enzymes, not separately listed on the basis of some function coupled with hydrolyzes of ATP, include enzymes dependent on Ca(2+), Mg(2+), anions, H(+) or DNA.
  • Formerly EC 3.6.1.4.
25 A0A085AFV9 A0A085GGV9 A0A085GJI9 A0A085GUQ6 A0A085H354 A0A085HKZ8 A0A085IG44 A0A085JCA8 A0A085U9Y5 A0A0B8Z9X9
(15 more...)
Nucleoside-triphosphate phosphatase. [EC: 3.6.1.15]
NTP + H(2)O = NDP + phosphate.
  • The enzyme is found in eukaryotes and thermophilic bacteria, but appears to be absent from mesophilic bacteria.
  • Also hydrolyzes nucleoside diphosphates, thiamine diphosphate and FAD.
  • The enzyme from the plant Pisum sativum (garden pea) is regulated by calmodulin.
22 A0A085AFV9 A0A085GGV9 A0A085GJI9 A0A085GUQ6 A0A085H354 A0A085HKZ8 A0A085IG44 A0A085JCA8 A0A0B8Z9X9 A0A0N0Z911
(12 more...)
Fe(3+)-transporting ATPase. [EC: 3.6.3.30]
ATP + H(2)O + Fe(3+)(Out) = ADP + phosphate + Fe(3+)(In).
  • A bacterial enzyme that imports ferric cations.
3 A0A1B1NP50 A0A1E3WNN7 F9RRL0