The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"P-loop containing nucleotide triphosphate hydrolases
".
FunFam 625019: Putative dynein heavy chain
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
ATP-dependent microtubule motor activity, minus-end-directed GO:0008569
Catalysis of movement along a microtubule toward the minus end, coupled to the hydrolysis of ATP.
|
6 | A0A0B4K614 (/ISS) A0A0B4K648 (/ISS) A0A0B4LH20 (/ISS) A8Y5B7 (/ISS) Q9GPN7 (/ISS) Q9VH97 (/ISS) |
|
ATPase activity, coupled GO:0042623
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction directly drives some other reaction, for example ion transport across a membrane.
|
6 | A0A0B4K614 (/ISS) A0A0B4K648 (/ISS) A0A0B4LH20 (/ISS) A8Y5B7 (/ISS) Q9GPN7 (/ISS) Q9VH97 (/ISS) |
|
ATPase activity, coupled GO:0042623
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction directly drives some other reaction, for example ion transport across a membrane.
|
2 | A8Y5B7 (/TAS) Q9GPN7 (/TAS) |
|
Microtubule motor activity GO:0003777
Catalysis of movement along a microtubule, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP).
|
1 | Q96JB1 (/NAS) |
There are 5 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cilium movement GO:0003341
The directed, self-propelled movement of a cilium.
|
6 | A0A0B4K614 (/ISS) A0A0B4K648 (/ISS) A0A0B4LH20 (/ISS) A8Y5B7 (/ISS) Q9GPN7 (/ISS) Q9VH97 (/ISS) |
|
Microtubule-based movement GO:0007018
A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules.
|
6 | A0A0B4K614 (/ISS) A0A0B4K648 (/ISS) A0A0B4LH20 (/ISS) A8Y5B7 (/ISS) Q9GPN7 (/ISS) Q9VH97 (/ISS) |
|
Sensory perception of sound GO:0007605
The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound.
|
4 | A0A0B4K614 (/IMP) A0A0B4K648 (/IMP) A0A0B4LH20 (/IMP) Q9VH97 (/IMP) |
|
Determination of heart left/right asymmetry GO:0061371
Determination of the asymmetric location of the heart with respect to the left and right halves of the organism.
|
2 | E7FFM4 (/IGI) K7DY80 (/IGI) |
|
Cilium-dependent cell motility GO:0060285
Cell motility due to the motion of one or more eukaryotic cilia. A eukaryotic cilium is a specialized organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
|
1 | Q96JB1 (/NAS) |
There are 9 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Outer dynein arm GO:0036157
Outer arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. Outer dynein arms contain 2-3 heavy chains, two or more intermediate chains and a cluster of 4-8 light chains. Inner and outer dynein arms have different functions in the generation of microtubule-based motility.
|
6 | A0A0B4K614 (/ISS) A0A0B4K648 (/ISS) A0A0B4LH20 (/ISS) A8Y5B7 (/ISS) Q9GPN7 (/ISS) Q9VH97 (/ISS) |
|
Dynein complex GO:0030286
Any of several large complexes that contain two or three dynein heavy chains and several light chains, and have microtubule motor activity.
|
4 | A0A0B4K614 (/ISS) A0A0B4K648 (/ISS) A0A0B4LH20 (/ISS) Q9VH97 (/ISS) |
|
Axonemal dynein complex GO:0005858
A dynein complex found in eukaryotic cilia and flagella; the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion.
|
2 | A8Y5B7 (/IMP) Q9GPN7 (/IMP) |
|
Axonemal dynein complex GO:0005858
A dynein complex found in eukaryotic cilia and flagella; the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion.
|
2 | A8Y5B7 (/ISS) Q9GPN7 (/ISS) |
|
Axonemal dynein complex GO:0005858
A dynein complex found in eukaryotic cilia and flagella; the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion.
|
1 | Q96JB1 (/NAS) |
|
Dynein complex GO:0030286
Any of several large complexes that contain two or three dynein heavy chains and several light chains, and have microtubule motor activity.
|
1 | Q96JB1 (/IDA) |
|
Dynein complex GO:0030286
Any of several large complexes that contain two or three dynein heavy chains and several light chains, and have microtubule motor activity.
|
1 | Q91XQ0 (/ISO) |
|
Outer dynein arm GO:0036157
Outer arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. Outer dynein arms contain 2-3 heavy chains, two or more intermediate chains and a cluster of 4-8 light chains. Inner and outer dynein arms have different functions in the generation of microtubule-based motility.
|
1 | Q91XQ0 (/ISM) |
|
Sperm principal piece GO:0097228
The segment of the sperm flagellum where the mitochondrial sheath ends, and the outer dense fibers (ODFs) associated with outer axonemal doublets 3 and 8 are replaced by the 2 longitudinal columns of the fibrous sheath (FS) which run the length of the principal piece and are stabilized by circumferential ribs. The principal piece makes up ~2/3 of the length of the sperm flagellum and is defined by the presence of the FS and of only 7 (rather than 9) ODFs which taper and then terminate near the distal end of the principal piece.
|
1 | Q91XQ0 (/IDA) |