The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 623887: GTPase IMAP family member 5

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q96F15 (/IPI)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
1 Q99MI6 (/IDA)

There are 18 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Temperature homeostasis GO:0001659
A homeostatic process in which an organism modulates its internal body temperature.
1 Q8K3L6 (/IMP)
Positive regulation of natural killer cell cytokine production GO:0002729
Any process that activates or increases the frequency, rate, or extent of natural killer cell cytokine production.
1 Q8K3L6 (/IMP)
Positive regulation of humoral immune response mediated by circulating immunoglobulin GO:0002925
Any process that activates or increases the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin.
1 Q8K3L6 (/IMP)
Positive regulation of calcium ion transport into cytosol GO:0010524
Any process that increases the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components.
1 Q8K3L6 (/IMP)
T cell differentiation GO:0030217
The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex.
1 Q8K3L6 (/IEP)
Negative regulation of interferon-gamma production GO:0032689
Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.
1 Q8K3L6 (/IMP)
Positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation GO:0032831
Any process that activates or increases the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells.
1 Q8K3L6 (/IMP)
Mitochondrial DNA inheritance GO:0033955
The process in which copies of the mitochondrial genome are distributed into daughter mitochondria upon mitochondrial fission.
1 Q99MI6 (/IMP)
Myeloid dendritic cell differentiation GO:0043011
The process in which a monocyte acquires the specialized features of a dendritic cell, an immunocompetent cell of the lymphoid and hemopoietic systems and skin.
1 Q8K3L6 (/IMP)
T cell homeostasis GO:0043029
The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.
1 Q8K3L6 (/IMP)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
1 Q8K3L6 (/IMP)
Negative regulation of nitric oxide biosynthetic process GO:0045019
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide.
1 Q8K3L6 (/IMP)
Positive regulation of gamma-delta T cell differentiation GO:0045588
Any process that activates or increases the frequency, rate or extent of gamma-delta T cell differentiation.
1 Q8K3L6 (/IMP)
Positive regulation of membrane potential GO:0045838
Any process that activates or increases the frequency, rate or extent of establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
1 Q8K3L6 (/IMP)
Positive regulation of natural killer cell mediated cytotoxicity GO:0045954
Any process that activates or increases the frequency, rate or extent of natural killer cell mediated cytotoxicity.
1 Q8K3L6 (/IMP)
Regulation of mitochondrial membrane permeability GO:0046902
Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane.
1 Q8K3L6 (/IMP)
Negative regulation of T cell activation GO:0050868
Any process that stops, prevents, or reduces the frequency, rate or extent of T cell activation.
1 Q8K3L6 (/IMP)
Negative regulation of lipid catabolic process GO:0050995
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids.
1 Q8K3L6 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 Q8K3L6 (/IDA) Q99MI6 (/IDA)
Mitochondrial outer membrane GO:0005741
The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.
1 Q99MI6 (/IDA)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
1 A0A087WTJ2 (/IDA)