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CATH Superfamily 3.40.50.300

P-loop containing nucleotide triphosphate hydrolases

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 620156: Cystic fibrosis transmembrane conductance regulato...

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Channel-conductance-controlling ATPase. [EC: 3.6.3.49]
ATP + H(2)O = ADP + phosphate.
  • An animal enzyme that is active in forming a chloride channel, the absence of which brings about cystic fibrosis.
  • It is also involved in the functioning of other transmembrane channels.
 190 A0A024R730 A0A060W0J2 A0A077EUX1 A0A087RGQ1 A0A087VFY7 A0A087Y9E9 A0A091DVI0 A0A091EMS0 A0A091GGX2 A0A091HSJ6
(180 more...)