The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 8016: Guanylate cyclase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Guanylate cyclase activity GO:0004383
Catalysis of the reaction: GTP = 3',5'-cyclic GMP + diphosphate.
4 C7LAF5 (/ISS) M9NFA6 (/ISS) Q8IQK2 (/ISS) Q9VU79 (/ISS)
Receptor activity GO:0004872
Combining with an extracellular or intracellular messenger to initiate a change in cell activity.
4 C7LAF5 (/ISS) M9NFA6 (/ISS) Q8IQK2 (/ISS) Q9VU79 (/ISS)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Golgi organization GO:0007030
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus.
4 C7LAF5 (/IMP) M9NFA6 (/IMP) Q8IQK2 (/IMP) Q9VU79 (/IMP)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
4 C7LAF5 (/ISS) M9NFA6 (/ISS) Q8IQK2 (/ISS) Q9VU79 (/ISS)
Positive regulation of cell proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
4 C7LAF5 (/IMP) M9NFA6 (/IMP) Q8IQK2 (/IMP) Q9VU79 (/IMP)
CGMP-mediated signaling GO:0019934
Any intracellular signal transduction in which the signal is passed on within the cell via cyclic GMP (cGMP). Includes production of cGMP, and downstream effectors that further transmit the signal within the cell.
4 C7LAF5 (/ISS) M9NFA6 (/ISS) Q8IQK2 (/ISS) Q9VU79 (/ISS)
Negative regulation of cell size GO:0045792
Any process that reduces cell size.
4 C7LAF5 (/IMP) M9NFA6 (/IMP) Q8IQK2 (/IMP) Q9VU79 (/IMP)
Positive regulation of mitotic cell cycle GO:0045931
Any process that activates or increases the rate or extent of progression through the mitotic cell cycle.
4 C7LAF5 (/IMP) M9NFA6 (/IMP) Q8IQK2 (/IMP) Q9VU79 (/IMP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
4 C7LAF5 (/ISS) M9NFA6 (/ISS) Q8IQK2 (/ISS) Q9VU79 (/ISS)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
4 C7LAF5 (/ISS) M9NFA6 (/ISS) Q8IQK2 (/ISS) Q9VU79 (/ISS)