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CATH Superfamily 3.40.50.2300

Response regulator

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 151799: Arsenate reductase ArsC

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Protein-tyrosine-phosphatase. [EC: 3.1.3.48]
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
  • Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.
 14 A0A0B7DB91 A0A0H2ZB53 A0A0H3R9G5 A0A0P1DC82 A0A0S4I1N6 A0A127MRH2 A0A157WRX6 A0A1D5C1G1 A0A1E9D0I2 A0A1F0I518
(4 more...)
Arsenate reductase (glutaredoxin). [EC: 1.20.4.1]
Arsenate + glutaredoxin = arsenite + glutaredoxin disulfide + H(2)O.
  • The enzyme is part of a system for detoxifying arsenate.
  • Although the arsenite formed is more toxic than arsenate, it can be extruded from some bacteria by EC 3.6.3.16; in other organisms, arsenite can be methylated by EC 2.1.1.137 in a pathway that produces non-toxic organoarsenical compounds (cf. EC 1.20.4.4).
  • Formerly EC 1.97.1.5.
 2 A0A143GI01 K9NJW3