The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 151424: Metabotropic glutamate receptor 5

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
G-protein coupled receptor activity GO:0004930
Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
5 A0A0B4KF15 (/IDA) A1Z7F4 (/IDA) A1Z7F5 (/IDA) B7YZT0 (/IDA) Q70GQ8 (/IDA)
Glutamate receptor activity GO:0008066
Combining with glutamate and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
2 H0ZKH5 (/IMP) H0ZRP5 (/IMP)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Phospholipase C-activating G-protein coupled receptor signaling pathway GO:0007200
The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent increase in the concentration of inositol trisphosphate (IP3) and diacylglycerol (DAG).
5 A0A0B4KF15 (/IDA) A1Z7F4 (/IDA) A1Z7F5 (/IDA) B7YZT0 (/IDA) Q70GQ8 (/IDA)
Adult feeding behavior GO:0008343
Feeding behavior in a fully developed and mature organism.
5 A0A0B4KF15 (/IMP) A1Z7F4 (/IMP) A1Z7F5 (/IMP) B7YZT0 (/IMP) Q70GQ8 (/IMP)
Response to insecticide GO:0017085
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insecticide stimulus. Insecticides are chemicals used to kill insects.
5 A0A0B4KF15 (/IDA) A1Z7F4 (/IDA) A1Z7F5 (/IDA) B7YZT0 (/IDA) Q70GQ8 (/IDA)
Response to insecticide GO:0017085
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insecticide stimulus. Insecticides are chemicals used to kill insects.
5 A0A0B4KF15 (/IMP) A1Z7F4 (/IMP) A1Z7F5 (/IMP) B7YZT0 (/IMP) Q70GQ8 (/IMP)
Negative regulation of excitatory postsynaptic potential GO:0090394
Any process that prevents the establishment or decreases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
2 H0ZKH5 (/IMP) H0ZRP5 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
5 A0A0B4KF15 (/IDA) A1Z7F4 (/IDA) A1Z7F5 (/IDA) B7YZT0 (/IDA) Q70GQ8 (/IDA)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
5 A0A0B4KF15 (/ISS) A1Z7F4 (/ISS) A1Z7F5 (/ISS) B7YZT0 (/ISS) Q70GQ8 (/ISS)
Dendrite GO:0030425
A neuron projection that has a short, tapering, often branched, morphology, receives and integrates signals from other neurons or from sensory stimuli, and conducts a nerve impulse towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
5 A0A0B4KF15 (/IDA) A1Z7F4 (/IDA) A1Z7F5 (/IDA) B7YZT0 (/IDA) Q70GQ8 (/IDA)