The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 151332: Glutamate receptor ionotropic, kainate 2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Kainate selective glutamate receptor activity GO:0015277
An ionotropic glutamate receptor activity that exhibits fast gating by glutamate, acts by opening a cation channel permeable to sodium and potassium, and for which kainate is an agonist.
4 A0A0B4KHJ0 (/ISS) Q0KI38 (/ISS) Q9TVI0 (/ISS) Q9VDH2 (/ISS)
Ionotropic glutamate receptor activity GO:0004970
Catalysis of the transmembrane transfer of an ion by a channel that opens when glutamate has been bound by the channel complex or one of its constituent parts.
2 Q0KI42 (/IC) Q9TVI0 (/IC)
Glutamate-gated calcium ion channel activity GO:0022849
Enables the transmembrane transfer of a calcium ion by a channel that opens when glutamate has been bound by the channel complex or one of its constituent parts.
2 Q0KI42 (/IDA) Q9TVI0 (/IDA)
Ionotropic glutamate receptor activity GO:0004970
Catalysis of the transmembrane transfer of an ion by a channel that opens when glutamate has been bound by the channel complex or one of its constituent parts.
1 Q9TVI0 (/IMP)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of synaptic activity GO:0060025
Any process that modulates the frequency, rate or extent of synaptic activity, the controlled release of neurotransmitters into the synaptic cleft and their subsequent detection by a postsynaptic cell.
4 A0A0B4KHJ0 (/ISS) Q0KI38 (/ISS) Q0KI42 (/ISS) Q9VDH2 (/ISS)
Calcium ion transport GO:0006816
The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 Q0KI42 (/IDA) Q9TVI0 (/IDA)
Neuromuscular synaptic transmission GO:0007274
The process of communication from a neuron to a muscle, across a synapse.
2 Q0KI42 (/IEP) Q9TVI0 (/IEP)
Regulation of BMP signaling pathway GO:0030510
Any process that modulates the frequency, rate or extent of the activity of any BMP receptor signaling pathway.
2 Q0KI42 (/IMP) Q9TVI0 (/IMP)
Synaptic transmission, glutamatergic GO:0035249
The process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.
2 Q0KI42 (/IC) Q9TVI0 (/IC)
Neuromuscular synaptic transmission GO:0007274
The process of communication from a neuron to a muscle, across a synapse.
1 Q9TVI0 (/IMP)
Rhythmic excitation GO:0043179
Any process involved in the generation of rhythmic, synchronous excitatory synaptic inputs in a neural circuit.
1 Q9TVI0 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
3 A0A0B4KHJ0 (/ISS) Q0KI38 (/ISS) Q9VDH2 (/ISS)
Ionotropic glutamate receptor complex GO:0008328
A multimeric assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand-gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex.
2 Q0KI42 (/IMP) Q9TVI0 (/IMP)
Muscle cell postsynaptic density GO:0097482
A postsynaptic specialization that is part of a neuromuscular junction.
2 Q0KI42 (/IDA) Q9TVI0 (/IDA)