The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 150824: Glutamate receptor, metabotropic 4

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 20 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glutamate receptor activity GO:0008066
Combining with glutamate and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
7 P31423 (/ISS) P35349 (/ISS) P91685 (/ISS) Q1ZZH0 (/ISS) Q5NCH9 (/ISS) Q68EF4 (/ISS) Q863I4 (/ISS)
G-protein coupled receptor activity GO:0004930
Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
4 P31423 (/ISS) P91685 (/ISS) Q1ZZH0 (/ISS) Q68EF4 (/ISS)
Group II metabotropic glutamate receptor activity GO:0001641
A G-protein coupled receptor that is activated by trans-1-aminocyclopentane-1,3-dicarboxylic acid (t-ACPD) and inhibits adenylate cyclase activity.
3 P91685 (/IDA) Q14BI2 (/IDA) Q9QYS2 (/IDA)
G-protein coupled receptor activity GO:0004930
Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
3 O15303 (/TAS) Q14416 (/TAS) Q14832 (/TAS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 O15303 (/IPI) P31421 (/IPI) Q14416 (/IPI)
Glutamate receptor activity GO:0008066
Combining with glutamate and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
3 O15303 (/TAS) Q14416 (/TAS) Q14832 (/TAS)
Group II metabotropic glutamate receptor activity GO:0001641
A G-protein coupled receptor that is activated by trans-1-aminocyclopentane-1,3-dicarboxylic acid (t-ACPD) and inhibits adenylate cyclase activity.
2 P31421 (/IMP) P31422 (/IMP)
Group III metabotropic glutamate receptor activity GO:0001642
A G-protein coupled receptor that is activated by L-AP-4 and inhibits adenylate cyclase activity.
2 Q5NCH9 (/TAS) Q68EF4 (/TAS)
Calcium channel regulator activity GO:0005246
Modulates the activity of a calcium channel.
2 Q14BI2 (/IDA) Q9QYS2 (/IDA)
Glutamate receptor activity GO:0008066
Combining with glutamate and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
2 O15303 (/IMP) Q14833 (/IMP)
Glutamate receptor activity GO:0008066
Combining with glutamate and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
2 Q5NCH9 (/ISO) Q68EF4 (/ISO)
Adenylate cyclase inhibiting G-protein coupled glutamate receptor activity GO:0001640
Combining with glutamate and transmitting the signal across the membrane by activating the alpha-subunit of an associated heterotrimeric G-protein complex to inhibit downstream adenylate cyclase activity.
1 P35349 (/IDA)
G-protein coupled receptor activity GO:0004930
Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
1 Q14833 (/IMP)
G-protein coupled receptor activity GO:0004930
Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
1 Q68EF4 (/ISO)
Calmodulin binding GO:0005516
Interacting selectively and non-covalently with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.
1 P31423 (/IPI)
Cholesterol binding GO:0015485
Interacting selectively and non-covalently with cholesterol (cholest-5-en-3-beta-ol); the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
1 P91685 (/IDA)
Glutamate binding GO:0016595
Interacting selectively and non-covalently with glutamate, the anion of 2-aminopentanedioic acid.
1 P91685 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 O15303 (/IPI)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 Q5NCH9 (/ISO)
Calcium-dependent protein binding GO:0048306
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in the presence of calcium.
1 P31423 (/IPI)

There are 53 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
G-protein coupled glutamate receptor signaling pathway GO:0007216
A series of molecular signals initiated by glutamate binding to a glutamate receptor on the surface of the target cell, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. Ends with regulation of a downstream cellular process, e.g. transcription.
4 P35349 (/ISS) P91685 (/ISS) Q5NCH9 (/ISS) Q863I4 (/ISS)
Adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway GO:0007196
The series of molecular signals generated as a consequence of a G-protein coupled glutamate receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP).
3 P31423 (/ISS) Q1ZZH0 (/ISS) Q68EF4 (/ISS)
Chemical synaptic transmission GO:0007268
The vesicular release of classical neurotransmitter molecules from a neuron, across a chemical synapse, the subsequent activation of neurotransmitter receptors of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
3 Q14416 (/TAS) Q14832 (/TAS) Q14833 (/TAS)
Detection of light stimulus involved in visual perception GO:0050908
The series of events involved in visual perception in which a light stimulus is received and converted into a molecular signal.
3 P35349 (/ISS) Q5NCH9 (/ISS) Q863I4 (/ISS)
Positive regulation of calcium ion import GO:0090280
Any process that increases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.
3 P35349 (/ISS) Q5NCH9 (/ISS) Q863I4 (/ISS)
Negative regulation of adenylate cyclase activity GO:0007194
Any process that stops, prevents, or reduces the frequency, rate or extent of adenylate cyclase activity.
2 Q14416 (/TAS) Q14832 (/TAS)
Learning GO:0007612
Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience.
2 P91685 (/IMP) Q68EF4 (/IMP)
Sensory perception of pain GO:0019233
The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process.
2 P31422 (/TAS) Q9QYS2 (/TAS)
Synaptic transmission, glutamatergic GO:0035249
The process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.
2 P31423 (/TAS) Q9QYS2 (/TAS)
Activation of MAPK activity GO:0000187
The initiation of the activity of the inactive enzyme MAP kinase (MAPK).
1 Q14833 (/IDA)
Activation of MAPK activity GO:0000187
The initiation of the activity of the inactive enzyme MAP kinase (MAPK).
1 Q68EF4 (/ISO)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
1 Q5NCH9 (/IGI)
G-protein coupled receptor signaling pathway GO:0007186
A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).
1 Q5NCH9 (/TAS)
Adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway GO:0007196
The series of molecular signals generated as a consequence of a G-protein coupled glutamate receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP).
1 P35349 (/IDA)
Adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway GO:0007196
The series of molecular signals generated as a consequence of a G-protein coupled glutamate receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP).
1 Q14833 (/IMP)
Adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway GO:0007196
The series of molecular signals generated as a consequence of a G-protein coupled glutamate receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP).
1 Q68EF4 (/ISO)
G-protein coupled glutamate receptor signaling pathway GO:0007216
A series of molecular signals initiated by glutamate binding to a glutamate receptor on the surface of the target cell, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. Ends with regulation of a downstream cellular process, e.g. transcription.
1 P91685 (/IDA)
G-protein coupled glutamate receptor signaling pathway GO:0007216
A series of molecular signals initiated by glutamate binding to a glutamate receptor on the surface of the target cell, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. Ends with regulation of a downstream cellular process, e.g. transcription.
1 O15303 (/IMP)
G-protein coupled glutamate receptor signaling pathway GO:0007216
A series of molecular signals initiated by glutamate binding to a glutamate receptor on the surface of the target cell, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. Ends with regulation of a downstream cellular process, e.g. transcription.
1 Q5NCH9 (/ISO)
G-protein coupled glutamate receptor signaling pathway GO:0007216
A series of molecular signals initiated by glutamate binding to a glutamate receptor on the surface of the target cell, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. Ends with regulation of a downstream cellular process, e.g. transcription.
1 O15303 (/TAS)
Chemical synaptic transmission GO:0007268
The vesicular release of classical neurotransmitter molecules from a neuron, across a chemical synapse, the subsequent activation of neurotransmitter receptors of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
1 P35349 (/IEP)
Chemical synaptic transmission GO:0007268
The vesicular release of classical neurotransmitter molecules from a neuron, across a chemical synapse, the subsequent activation of neurotransmitter receptors of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
1 Q68EF4 (/IMP)
Neurotransmitter secretion GO:0007269
The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium regualated exocytosis during synaptic transmission.
1 Q14833 (/TAS)
Neuromuscular junction development GO:0007528
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction.
1 P91685 (/IMP)
Visual perception GO:0007601
The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.
1 Q5NCH9 (/TAS)
Short-term memory GO:0007614
The memory process that deals with the storage, retrieval and modification of information received a short time (up to about 30 minutes) ago. This type of memory is typically dependent on direct, transient effects of second messenger activation.
1 P91685 (/IMP)
Long-term memory GO:0007616
The memory process that deals with the storage, retrieval and modification of information a long time (typically weeks, months or years) after receiving that information. This type of memory is typically dependent on gene transcription regulated by second messenger activation.
1 P91685 (/IMP)
Locomotory behavior GO:0007626
The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.
1 Q5NCH9 (/IMP)
Male courtship behavior GO:0008049
The behavior of a male, for the purpose of attracting a sexual partner. An example of this process is found in Drosophila melanogaster.
1 P91685 (/IMP)
Negative regulation of cell proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
1 P31423 (/TAS)
Detection of visible light GO:0009584
The series of events in which a visible light stimulus is received by a cell and converted into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm.
1 O15303 (/TAS)
Positive regulation of lipid storage GO:0010884
Any process that increases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.
1 Q09630 (/IGI)
Glutamate secretion GO:0014047
The controlled release of glutamate by a cell. The glutamate is the most abundant excitatory neurotransmitter in the nervous system.
1 P31421 (/IDA)
Gamma-aminobutyric acid secretion GO:0014051
The regulated release of gamma-aminobutyric acid by a cell or a tissue. The gamma-aminobutyric acid is the principal inhibitory neurotransmitter in the brain but is also found in several extraneural tissues.
1 P31423 (/TAS)
Neuron projection development GO:0031175
The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
1 P31423 (/TAS)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
1 P31423 (/TAS)
Positive regulation of MAPK cascade GO:0043410
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade.
1 Q14833 (/IEP)
Regulation of neuron apoptotic process GO:0043523
Any process that modulates the occurrence or rate of cell death by apoptotic process in neurons.
1 P31423 (/NAS)
Regulation of neuron apoptotic process GO:0043523
Any process that modulates the occurrence or rate of cell death by apoptotic process in neurons.
1 Q14833 (/TAS)
Regulation of neurotransmitter secretion GO:0046928
Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell.
1 P31421 (/NAS)
Modulation of synaptic transmission GO:0050804
Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission.
1 P31422 (/IDA)
Negative regulation of synaptic transmission GO:0050805
Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.
1 P31423 (/TAS)
Detection of light stimulus involved in visual perception GO:0050908
The series of events involved in visual perception in which a light stimulus is received and converted into a molecular signal.
1 O15303 (/IMP)
Detection of light stimulus involved in visual perception GO:0050908
The series of events involved in visual perception in which a light stimulus is received and converted into a molecular signal.
1 Q5NCH9 (/ISO)
Sensory perception of light stimulus GO:0050953
The series of events required for an organism to receive a sensory light stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
1 Q5NCH9 (/IMP)
Regulation of sensory perception of pain GO:0051930
Any process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal.
1 Q9QYS2 (/NAS)
Synaptic transmission, GABAergic GO:0051932
The process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).
1 P31423 (/TAS)
Regulation of synaptic transmission, glutamatergic GO:0051966
Any process that modulates the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.
1 P91685 (/IMP)
Regulation of synaptic transmission, glutamatergic GO:0051966
Any process that modulates the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.
1 P31421 (/NAS)
Retina development in camera-type eye GO:0060041
The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates.
1 Q5NCH9 (/IMP)
Terminal button organization GO:0072553
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a terminal button. A terminal button is the terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters.
1 P91685 (/IMP)
Positive regulation of calcium ion import GO:0090280
Any process that increases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.
1 O15303 (/IMP)
Positive regulation of calcium ion import GO:0090280
Any process that increases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.
1 Q5NCH9 (/ISO)

There are 33 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
5 O15303 (/TAS) P31421 (/TAS) Q14416 (/TAS) Q14832 (/TAS) Q14833 (/TAS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
4 O15303 (/TAS) Q14416 (/TAS) Q14832 (/TAS) Q14833 (/TAS)
Golgi membrane GO:0000139
The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
3 P35349 (/ISS) Q5NCH9 (/ISS) Q863I4 (/ISS)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
3 P35349 (/ISS) Q5NCH9 (/ISS) Q863I4 (/ISS)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
3 O15303 (/IDA) P91685 (/IDA) Q14833 (/IDA)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
3 P35349 (/ISS) Q5NCH9 (/ISS) Q863I4 (/ISS)
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
3 Q14BI2 (/IDA) Q68EF4 (/IDA) Q9QYS2 (/IDA)
Intracellular GO:0005622
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
2 P31421 (/IDA) Q14833 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 P91685 (/IDA) Q9QYS2 (/IDA)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 Q5NCH9 (/ISO) Q68EF4 (/ISO)
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
2 P31421 (/IDA) Q9QYS2 (/IDA)
Presynaptic membrane GO:0042734
A specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction; many synaptic junctions exhibit structural presynaptic characteristics, such as conical, electron-dense internal protrusions, that distinguish it from the remainder of the axon plasma membrane.
2 P31421 (/IDA) Q9QYS2 (/IDA)
Golgi membrane GO:0000139
The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
1 O15303 (/IDA)
Golgi membrane GO:0000139
The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
1 Q5NCH9 (/ISO)
Intracellular GO:0005622
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
1 Q68EF4 (/ISO)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
1 O15303 (/IDA)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
1 Q5NCH9 (/ISO)
Postsynaptic density GO:0014069
An electron dense network of proteins within and adjacent to the postsynaptic membrane in asymetric synapses. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
1 Q9QYS2 (/IDA)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 P91685 (/ISS)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 P35349 (/TAS)
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
1 Q14833 (/IDA)
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
1 Q68EF4 (/ISO)
New growing cell tip GO:0035841
A cell tip that was newly formed at the last cell division, and that has started to grow after the cell has activated bipolar cell growth (i.e. in which new end take-off, NETO, has taken place). New end take-off is when monopolar cells initiate bipolar growth.
1 Q5NCH9 (/IDA)
G-protein coupled receptor homodimeric complex GO:0038038
A protein complex that contains two G-protein coupled receptors (GPCRs) of the same subtype. Formation of a GPCR homodimer may be important for the transport of newly formed receptors to the cell surface, and the function of the receptor.
1 P91685 (/ISS)
Terminal bouton GO:0043195
Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it.
1 P31423 (/IDA)
Dendritic spine GO:0043197
A small, membranous protrusion from a dendrite that forms a postsynaptic compartment - typically receiving input from a single presynapse. They function as partially isolated biochemical and an electrical compartments. Spine morphology is variable including \thin\, \stubby\, \mushroom\, and \branched\, with a continuum of intermediate morphologies. They typically terminate in a bulb shape, linked to the dendritic shaft by a restriction. Spine remodeling is though to be involved in synaptic plasticity.
1 Q9QYS2 (/IDA)
Dendritic shaft GO:0043198
Cylindric portion of the dendrite, directly stemming from the perikaryon, and carrying the dendritic spines.
1 P31423 (/IDA)
Membrane raft GO:0045121
Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
1 P91685 (/IDA)
Postsynaptic membrane GO:0045211
A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane.
1 Q9QYS2 (/IDA)
Postsynaptic membrane GO:0045211
A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane.
1 Q5NCH9 (/TAS)
Presynaptic active zone GO:0048786
A specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, and a specialized cortical cytoskeletal matrix.
1 Q9QYS2 (/NAS)
Presynaptic active zone membrane GO:0048787
The membrane portion of the presynaptic active zone; it is the site where docking and fusion of synaptic vesicles occurs for the release of neurotransmitters.
1 P31423 (/IDA)
Astrocyte projection GO:0097449
A prolongation or process extending from the soma of an astrocyte and wrapping around neurons.
1 P31422 (/IDA)