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CATH Superfamily 3.40.50.2300

Response regulator

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 141871: Fructose-like phosphotransferase enzyme IIB compon...

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Transferred entry: 2.7.1.191, 2.7.1.192, 2.7.1.193, 2.7.1.194, 2.7.1.195, 2.7.1.196, 2.7.1.197, 2.7.1.198, 2.7.1.199, 2.7.1.200, 2.7.1.201, 2.7.1.202, 2.7.1.203, 2.7.1.204, 2.7.1.205, 2.7.1.206, 2.7.1.207 and 2.7.1.208. [EC: 2.7.1.69]
    		530 A0A017I5Q2 A0A017I5Q2 A0A023Z6P2 A0A023Z6P2 A0A025C7I6 A0A025C7I6 A0A026RXS0 A0A026RXS0 A0A026URL3 A0A026URL3
    (520 more...)
    Protein-N(pi)-phosphohistidine--D-mannose phosphotransferase. [EC: 2.7.1.191]
    [Protein]-N(pi)-phospho-L-histidine + D-mannose(Side 1) = [protein]-L- histidine + D-mannose 6-phosphate(Side 2).
    • This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).
    • The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.
    • The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.
    • Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency.
    • The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.
    • Formerly EC 2.7.1.69.
    		 510 A0A017I5Q2 A0A017I5Q2 A0A023Z6P2 A0A023Z6P2 A0A025C7I6 A0A025C7I6 A0A026RXS0 A0A026RXS0 A0A026URL3 A0A026URL3
    (500 more...)
    Protein-N(pi)-phosphohistidine--D-fructose phosphotransferase. [EC: 2.7.1.202]
    [Protein]-N(pi)-phospho-L-histidine + D-fructose(Side 1) = [protein]-L- histidine + D-fructose 1-phosphate(Side 2).
    • This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).
    • The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.
    • The phosphate donor, which is shared among the different systems, is usually a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.
    • The enzyme from the bacterium Escherichia coli is an exception, since it is phosphorylated directly by EC 2.7.3.9.
    • The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.
    • Formerly EC 2.7.1.69.
    		 140 A0A023Z6P2 A0A023Z6P2 A0A025C7I6 A0A025C7I6 A0A029K185 A0A029K185 A0A029L841 A0A029L841 A0A069XKP6 A0A069XKP6
    (130 more...)