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CATH Superfamily 3.40.50.2300

Response regulator

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 13866: Cyclic di-GMP phosphodiesterase response regulator...

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Cyclic-guanylate-specific phosphodiesterase. [EC: 3.1.4.52]
Cyclic di-3',5'-guanylate + H(2)O = 5'-phosphoguanylyl(3'->5')guanosine.
  • Inhibited by Ca(2+) and Zn(2+).
  • Linearizes cyclic di-3',5'-guanylate, the product of EC 2.7.7.65 and an allosteric activator of EC 2.4.1.12 rendering it inactive.
  • It is the balance between these two enzymes that determines the cellular level of cyclic di-3',5'-guanylate.
 17 A0A031HCV4 A0A0D0LV32 A0A0D5UIK4 A0A0K2ZC56 A0A0K2ZTF5 A0A0M0NGQ5 A0A0U4YKZ4 A0A0U5HKJ6 A0A1M4IYJ7 A0A1M4J8H8
(7 more...)
Protein-glutamate methylesterase. [EC: 3.1.1.61]
Protein L-glutamate O(5)-methyl ester + H(2)O = protein L-glutamate + methanol.
  • Hydrolyzes the products of EC 2.1.1.77, EC 2.1.1.78, EC 2.1.1.80 and EC 2.1.1.100.
 4 A0A077S3F5 B8LAP5 H1XLS4 H8FFU3