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CATH Superfamily 3.40.50.2030

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1765: Carbon-monoxide dehydrogenase, catalytic subunit

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Anaerobic carbon-monoxide dehydrogenase. [EC: 1.2.7.4]
CO + H(2)O + 2 oxidized ferredoxin = CO(2) + 2 reduced ferredoxin + 2 H(+).
  • This prokaryotic enzyme catalyzes the reversible reduction of CO(2) to CO.
  • The electrons are transferred to redox proteins such as ferredoxin.
  • In purple sulfur bacteria and methanogenic archaea it catalyzes the oxidation of CO to CO(2), which is incorporated by the Calvin-Benson- Basham cycle or released, respectively.
  • In acetogenic and sulfate-reducing microbes it catalyzes the reduction of CO(2) to CO, which is incorporated into acetyl CoA by EC 2.3.1.169, with which the enzyme forms a tight complex in those organisms.
  • In purple sulfur bacteria the enzyme forms complexes with the Ni-Fe-S protein EC 1.12.7.2 which catalyze the overall reaction: CO + H(2)O = CO(2) + H(2).
  • Cf. EC 1.2.5.3.
  • Formerly EC 1.2.99.2.
 10 A0A075WGA8 A0A076LGK3 A0A101E031 C9RFY5 D3S5K4 F6BB28 H1L075 O28429 Q58138 Q8TXX3