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CATH Superfamily 3.40.50.2020

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 18123: Uridine kinase/uracil phosphoribosyltransferase 1

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Uridine kinase. [EC: 2.7.1.48]
(1) ATP + uridine = ADP + UMP. (2) ATP + cytidine = ADP + CMP.
  • Cytidine can act as acceptor.
  • GTP and ITP can act as donors.
 299 A0A022QIW2 A0A022RWE5 A0A022S0F1 A0A059AGS7 A0A059BQH5 A0A059BWI0 A0A061EEE8 A0A061EJT9 A0A061FBQ2 A0A061RGM8
(289 more...)
Uracil phosphoribosyltransferase. [EC: 2.4.2.9]
UMP + diphosphate = uracil + 5-phospho-alpha-D-ribose 1-diphosphate.
    		 54 A0A023BAY2 A0A060T8B5 A0A074SVN4 A0A075ASF6 A0A086KIF1 A0A086L0R0 A0A086LHA6 A0A086MAU3 A0A086QAK2 A0A086QZ53
    (44 more...)
    Fructose-bisphosphate aldolase. [EC: 4.1.2.13]
    D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate.
    • Also acts on (3S,4R)-ketose 1-phosphates.
    • The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.
    • Formerly EC 4.1.2.7.
    		 5 A0A078DY92 A0A0B2QUU5 A0A0B2SI36 A0A0D3A6M9 A0A165YXY3