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CATH Superfamily 3.40.50.2000

Glycogen Phosphorylase B;

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Glycogen Phosphorylase B;
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 96637: Alpha-1,3/1,6-mannosyltransferase ALG2

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
GDP-Man:Man(1)GlcNAc(2)-PP-dolichol alpha-1,3-mannosyltransferase. [EC: 2.4.1.132]
GDP-D-mannose + D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc- diphosphodolichol = GDP + D-Man-alpha-(1->3)-D-Man-beta-(1->4)-D-GlcNAc- beta-(1->4)-GlcNAc-diphosphodolichol.
  • The biosynthesis of asparagine-linked glycoproteins utilizes a dolichyl diphosphate-linked glycosyl donor, which is assembled by the series of membrane-bound glycosyltransferases that comprise the dolichol pathway.
  • Alg2 mannosyltransferase from Saccharomyces cerevisiae carries out an alpha-1,3-mannosylation of D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D- GlcNAc-diphosphodolichol, followed by an alpha-1,6-mannosylation (cf. EC 2.4.1.257), to form the first branched pentasaccharide intermediate of the dolichol pathway.
 28 A0A024R184 A0A060TBP7 A0A0B0DNZ3 A0A0L1HL99 A0A1H6PVC8 A3LTA0 B3M7E0 B3NF31 B4KWS2 B4LGX4
(18 more...)
GDP-Man:Man(2)GlcNAc(2)-PP-dolichol alpha-1,6-mannosyltransferase. [EC: 2.4.1.257]
GDP-D-mannose + D-Man-alpha-(1->3)-D-Man-beta-(1->4)-D-GlcNAc-beta- (1->4)-D-GlcNAc-diphosphodolichol = GDP + D-Man-alpha-(1->3)-(D-Man- alpha-(1->6))-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc- diphosphodolichol.
  • The biosynthesis of asparagine-linked glycoproteins utilizes a dolichyl diphosphate-linked glycosyl donor, which is assembled by the series of membrane-bound glycosyltransferases that comprise the dolichol pathway.
  • Alg2 mannosyltransferase from Saccharomyces cerevisiae carries out an alpha-1,3-mannosylation (cf. EC 2.4.1.132) of D-Man-beta-(1->4)-D- GlcNAc-beta-(1->4)-GlcNAc-diphosphodolichol, followed by an alpha- 1,6-mannosylation, to form the first branched pentasaccharide intermediate of the dolichol pathway.
 17 A0A024R184 A0A0B0DNZ3 A0A1H6PVC8 C7GW45 N1P9R0 O94738 P43636 Q59LF2 Q6BVA4 Q6C3V7
(7 more...)
Initiation-specific alpha-1,6-mannosyltransferase. [EC: 2.4.1.232]
Transfers an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->6)-D-mannosyl-D-mannose linkage.
  • In Saccharomyces cerevisiae, this enzyme catalyzes an essential step in the outer chain elongation of N-linked oligosaccharides.
  • Man(8)GlcNAc and Man(9)GlcNAc are equally good substrates.
 10 A0A060TBP7 A0A0L1HL99 B3M7E0 B3NF31 B4KWS2 B4LGX4 B4N6C6 B4PCV1 B4QP22 Q29E27