The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Glycogen Phosphorylase B;
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 96346: UDP-glucose:flavonoid 3-O-glucosyltransferase

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Anthocyanidin 3-O-glucosyltransferase. [EC: 2.4.1.115]
UDP-D-glucose + an anthocyanidin = UDP + an anthocyanidin-3-O-beta-D- glucoside.
  • The anthocyanidin compounds cyanidin, delphinidin, peonidin and to a lesser extent pelargonidin can act as substrates.
  • Does not catalyze glucosylation of the 5-position of cyanidin and does not act on flavanols such as quercetin and kaempferol (cf. EC 2.4.1.91).
  • In conjunction with EC 1.14.11.19, it is involved in the conversion of leucoanthocyanidin into anthocyanidin 3-glucoside.
  • It may act on the pseudobase precursor of the anthocyanidin rather than on the anthocyanidin itself.
  • Formerly EC 2.4.1.233.
10 F2VR51 F2VR51 P51094 P51094 Q5UL10 Q5UL10 Q66PF5 Q66PF5 Q96493 Q96493
Flavonol 3-O-glucosyltransferase. [EC: 2.4.1.91]
UDP-glucose + a flavonol = UDP + a flavonol 3-O-D-glucoside.
  • Acts on a variety of flavonols, including quercetin and quercetin 7-O-glucoside.
  • Different from EC 2.4.1.81.
6 A0A151SRQ0 A0A151SRQ0 Q9LFJ8 Q9LFJ8 W8PUE7 W8PUE7
Flavonol-3-O-glucoside L-rhamnosyltransferase. [EC: 2.4.1.159]
UDP-beta-L-rhamnose + a flavonol 3-O-beta-D-glucoside = UDP + a flavonol 3-O-(alpha-L-rhamnosyl-(1->6)-beta-D-glucoside).
  • A configuration-inverting rhamnosyltransferase that converts flavonol 3-O-glucosides to 3-O-rutinosides.
  • Also acts, more slowly, on rutin, quercetin 3-O-galactoside and flavonol 3-O-rhamnosides.
4 Q9S9P6 Q9S9P6 W8PVA4 W8PVA4
Kaempferol 3-O-galactosyltransferase. [EC: 2.4.1.234]
UDP-alpha-D-galactose + kaempferol = UDP + kaempferol 3-O-beta-D- galactoside.
  • Acts on the endogenous flavonols kaempferol and quercetin, to a lesser extent on myricetin and fisetin, and weakly on galangin and isorhamnetin.
  • The reaction can occur equally well in both directions.
2 Q9SBQ8 Q9SBQ8