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CATH Superfamily 3.40.50.20

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 15532: Putative phosphoribosylglycinamide formyltransfera...

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Phosphoribosylglycinamide formyltransferase. [EC: 2.1.2.2]
10-formyltetrahydrofolate + N(1)-(5-phospho-D-ribosyl)glycinamide = tetrahydrofolate + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide.
    		 4 A0A1L8CK92 A0A1L9EY51 A0A1M5VMQ7 H8IA92
    Acetate kinase. [EC: 2.7.2.1]
    ATP + acetate = ADP + acetyl phosphate.
    • While purified enzyme from Escherichia coli is specific for acetate, others have found that the enzyme can also use propanoate as a substrate, but more slowly.
    • Acetate can be converted into the key metabolic intermediate acetyl- CoA by coupling acetate kinase with EC 2.3.1.8.
    • Both this enzyme and EC 2.7.2.15 play important roles in the production of propanoate.
    		 2 A0A1N7RZN8 A0A1N7S079