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CATH Superfamily 3.40.50.20

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 10120: Lysine biosynthesis enzyme LysX

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
[Lysine-biosynthesis-protein LysW]--L-2-aminoadipate ligase. [EC: 6.3.2.43]
ATP + [lysine-biosynthesis-protein LysW]-C-terminal-L-glutamate + L-2- aminoadipate = ADP + phosphate + [lysine-biosynthesis-protein LysW]-C- terminal-gamma-(L-2-aminoadip-2-yl)-L-glutamate.
  • The enzymes from the thermophilic bacterium Thermus thermophilus and the thermophilic archaea Sulfolobus acidocaldarius and Sulfolobus tokodaii protect the amino group of L-2-aminoadipate by conjugation to the carrier protein LysW.
  • This reaction is part of the lysine biosynthesis pathway in these organisms.
  • Formerly EC 6.3.2.n4.
 2 Q5SH23 Q5SH23