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CATH Superfamily 3.40.50.1820

Alpha/Beta hydrolase fold, catalytic domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 46933: Putative 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1...

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase. [EC: 4.2.99.20]
5-enolpyruvoyl-6-hydroxy-2-succinylcyclohex-3-ene-1-carboxylate = (1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate + pyruvate.
  • Involved in the biosynthesis of vitamin K2 (menaquinone).
  • In most anaerobes and all Gram-positive aerobes, menaquinone is the sole electron transporter in the respiratory chain and is essential for their survival.
  • It had previously been thought that the reactions carried out by this enzyme and EC 2.2.1.9 were carried out by a single enzyme but this has since been disproved.
  • Formerly EC 2.5.1.64 and EC 4.2.99.n1.
 23 A0A0D1L5B8 A0A0K6JIK1 A0A0K6JNE4 A0A0K6L362 A0A0K6L758 A0A0M0KPS6 A0A0T8PI74 A0A125ULH2 A0A162RYI1 A0A165AMR0
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