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CATH Superfamily 3.40.50.1820

Alpha/Beta hydrolase fold, catalytic domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 36914: Esterase/lipase LipF

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Monoterpene epsilon-lactone hydrolase. [EC: 3.1.1.83]
Isoprop(en)ylmethyloxepan-2-one + H(2)O = 6-hydroxyisoprop(en)ylmethylhexanoate.
  • Catalyzes the ring opening of epsilon-lactones which are formed during degradation of dihydrocarveol by the Gram-positive bacterium Rhodococcus erythropolis DCL14.
  • Also acts on ethyl caproate, indicating that it is an esterase with a preference for lactones (internal cyclic esters).
  • Not stereoselective.
 10 A0A0E7ZJJ7 A0A0E8UG25 A0A0G4DUZ2 A0A0H3LM13 A0A0T9B5Q9 A0A120IQD5 A0A120J366 A0A1K2XF19 A0A1K4EJF0 Q7D5F9
Carboxylesterase. [EC: 3.1.1.1]
A carboxylic ester + H(2)O = an alcohol + a carboxylate.
  • Wide specificity; also hydrolyzes vitamin A esters.
  • The enzymes from microsomes also catalyze the reactions of EC 3.1.1.2, EC 3.1.1.5, EC 3.1.1.6, EC 3.1.1.23, EC 3.1.1.28, EC 3.1.2.2, EC 3.5.1.4, and EC 3.5.1.13.
  • Formerly EC 3.1.1.12.
 8 A0A0H3M9N0 A0A197J102 A0A1L7FTD6 A5U8G2 F8M7S2 I6YGA0 M8CH56 O06350