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CATH Superfamily 3.40.50.1820

Alpha/Beta hydrolase fold, catalytic domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 30439: Luciferase/green fluorescent protein fusion protei...

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Renilla-luciferin 2-monooxygenase. [EC: 1.13.12.5]
Renilla luciferin + O(2) = oxidized Renilla luciferin + CO(2) + light.
  • From the soft coral coelenterate Renilla reniformis.
  • The luciferin is bound to a luciferin-binding protein (BP-LH2).
  • The bioluminescent reaction between the luciferin complex, luciferase and oxygen is triggered by calcium ions.
  • In vivo, the excited state luciferin--luciferase complex undergoes the process of nonradiative energy transfer to an accessory protein, Renilla green fluorescent protein, which results in green bioluminescence.
  • In vitro, Renilla luciferase emits blue light in the absence of any green fluorescent protein.
 2 C9V492 P27652