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CATH Superfamily 3.40.50.1820

Alpha/Beta hydrolase fold, catalytic domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 115731: Esterase, PHB depolymerase family

There are 10 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Feruloyl esterase. [EC: 3.1.1.73]
Feruloyl-polysaccharide + H(2)O = ferulate + polysaccharide.
  • Catalyzes the hydrolysis of the 4-hydroxy-3-methoxycinnamoyl (feruloyl) group from an esterified sugar, which is usually arabinose in 'natural' substrates.
  • p-nitrophenol acetate and methyl ferulate are poorer substrates.
  • All microbial ferulate esterases are secreted into the culture medium.
  • They are sometimes called hemicellulase accessory enzymes, since they help xylanases and pectinases to break down plant cell wall hemicellulose.
 56 A0A084FV25 A0A084FV25 A0A084GDZ3 A0A084GDZ3 A0A0B0DY96 A0A0B0DY96 A0A0K1ED40 A0A0K1ED40 A0A0N0N862 A0A0N0N862
(46 more...)
Acetylxylan esterase. [EC: 3.1.1.72]
Deacetylation of xylans and xylo-oligosaccharides.
  • Catalyzes the hydrolysis of acetyl groups from polymeric xylan, acetylated xylose, acetylated glucose, alpha-napthyl acetate, p-nitrophenyl acetate but not from triacetylglycerol.
  • Does not act on acetylated mannan or pectin.
 56 A0A084FV25 A0A084FV25 A0A084G0I1 A0A084G0I1 A0A084GBL8 A0A084GBL8 A0A084GEM9 A0A084GEM9 A0A0F4Z2H9 A0A0F4Z2H9
(46 more...)
Endo-1,4-beta-xylanase. [EC: 3.2.1.8]
Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.
    		 18 A0A066UJC4 A0A066UJC4 A0A0H3DDB2 A0A0H3DDB2 A0A177HUP0 A0A177HUP0 A0A1K1SSZ2 A0A1K1SSZ2 A0A1M4EBG7 A0A1M4EBG7
    (8 more...)
    Cellulose 1,4-beta-cellobiosidase (non-reducing end). [EC: 3.2.1.91]
    Hydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose and cellotetraose, releasing cellobiose from the non-reducing ends of the chains.
      		 12 A0A0U5M180 A0A0U5M180 A0A100JGF8 A0A100JGF8 A0A100JNL4 A0A100JNL4 A0A1D8GAK8 A0A1D8GAK8 A0A1K2FNM5 A0A1K2FNM5
      (2 more...)
      Cellulase. [EC: 3.2.1.4]
      Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.
      • Will also hydrolyze 1,4-linkages in beta-D-glucans also containing 1,3-linkages.
      		 6 A0A0N0N862 A0A0N0N862 A0A0N0NC74 A0A0N0NC74 A0A0T9M720 A0A0T9M720
      Poly(3-hydroxybutyrate) depolymerase. [EC: 3.1.1.75]
      ((R)-3-hydroxybutanoate)(n) + H(2)O = ((R)-3-hydroxybutanoate)(n-1 to 5) + ((R)-3-hydroxybutanoate)(1-5).
      • Reaction also occurs with esters of other short-chain-length (C(1)- C(5)) hydroxyalkanoic acids (HA).
      • There are two types of polymers: native (intracellular) granules are amorphous and have an intact surface layer; denatured (extracellular) granules either have no surface layer or a damaged surface layer and are partially crystalline.
      		 6 A0A0N1G0W0 A0A0N1G0W0 E8WE68 E8WE68 I0L979 I0L979
      Beta-diketone hydrolase. [EC: 3.7.1.7]
      Nonane-4,6-dione + H(2)O = pentan-2-one + butanoate.
      • Also acts on the product of the action of EC 1.1.3.18 on polyvinyl alcohols.
      • Involved in the bacterial degradation of polyvinyl alcohol.
      		 6 A0A0X8R4I9 A0A0X8R4I9 Q588Z2 Q588Z2 Q9LCQ7 Q9LCQ7
      Chitinase. [EC: 3.2.1.14]
      Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta- linkages in chitin and chitodextrins.
      • The enzyme binds to chitin and randomly cleaves glycosidic linkages in chitin and chitodextrins in a non-processive mode, generating chitooligosaccharides and free ends on which exo-chitinases and exo- chitodextrinases can act.
      • Activity is greatly stimulated in the presence of EC 1.14.99.53, which attacks the crystalline structure of chitin and makes the polymer more accesible to the chitinase.
      • Cf. EC 3.2.1.202.
      		 2 A0A1K2FPK3 A0A1K2FPK3
      Carboxylesterase. [EC: 3.1.1.1]
      A carboxylic ester + H(2)O = an alcohol + a carboxylate.
      • Wide specificity; also hydrolyzes vitamin A esters.
      • The enzymes from microsomes also catalyze the reactions of EC 3.1.1.2, EC 3.1.1.5, EC 3.1.1.6, EC 3.1.1.23, EC 3.1.1.28, EC 3.1.2.2, EC 3.5.1.4, and EC 3.5.1.13.
      • Formerly EC 3.1.1.12.
      		 2 A0A0B7F1R7 A0A0B7F1R7
      Hydroxymethylglutaryl-CoA reductase (NADPH). [EC: 1.1.1.34]
      (R)-mevalonate + CoA + 2 NADP(+) = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADPH.
      • The enzyme is inactivated by EC 2.7.11.31 and reactivated by EC 3.1.3.47.
      		 2 A0A0G4KL57 A0A0G4KL57