The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 115306: Lysosomal thioesterase PPT2 homolog

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Palmitoyl-(protein) hydrolase activity GO:0008474
Catalysis of the reaction: palmitoyl-protein + H2O = palmitate + protein.
1 Q9VKH6 (/ISS)
Thiolester hydrolase activity GO:0016790
Catalysis of the reaction: RCO-SR' + H2O = RCOOH + HSR'. This reaction is the hydrolysis of a thiolester bond, an ester formed from a carboxylic acid and a thiol (i.e., RCO-SR'), such as that found in acetyl-coenzyme A.
1 Q9UMR5 (/NAS)
Palmitoyl hydrolase activity GO:0098599
Catalysis of a hydrolase reaction that removes a palmitoyl moiety from some substrate.
1 Q9UMR5 (/IDA)
Palmitoyl hydrolase activity GO:0098599
Catalysis of a hydrolase reaction that removes a palmitoyl moiety from some substrate.
1 Q9VKH6 (/IGI)
Palmitoyl hydrolase activity GO:0098599
Catalysis of a hydrolase reaction that removes a palmitoyl moiety from some substrate.
1 O35448 (/ISO)
Palmitoyl hydrolase activity GO:0098599
Catalysis of a hydrolase reaction that removes a palmitoyl moiety from some substrate.
1 Q9UMR5 (/TAS)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Fatty-acyl-CoA biosynthetic process GO:0046949
The chemical reactions and pathways resulting in the formation of a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group.
1 Q9UMR5 (/TAS)
Macromolecule depalmitoylation GO:0098734
The removal of palymitoyl groups from a macromolecule.
1 Q9VKH6 (/IGI)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Lysosome GO:0005764
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
1 Q9VKH6 (/IDA)
Lysosome GO:0005764
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
1 Q9UMR5 (/NAS)
Lysosomal lumen GO:0043202
The volume enclosed within the lysosomal membrane.
1 Q9UMR5 (/TAS)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
1 Q9UMR5 (/IDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
1 O35448 (/ISO)