View in Gene3D

CATH Superfamily 3.40.50.1820

Alpha/Beta hydrolase fold, catalytic domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 115014: Group XV phospholipase A2

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Phosphatidylcholine--sterol O-acyltransferase. [EC: 2.3.1.43]
Phosphatidylcholine + a sterol = 1-acylglycerophosphocholine + a sterol ester.
  • Palmitoyl, oleoyl, and linoleoyl can be transferred; a number of sterols, including cholesterol, can act as acceptors.
  • The bacterial enzyme also catalyzes the reactions of EC 3.1.1.4 and EC 3.1.1.5.
 28 A0A140VK24 A0A140VK24 E3TFA6 E3TFA6 H2QBD3 H2QBD3 O35502 O35502 O35573 O35573
(18 more...)
Phospholipase A(2). [EC: 3.1.1.4]
Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate.
  • Also acts on phosphatidylethanolamine, choline plasmalogen and phosphatides, removing the fatty acid attached to the 2-position.
 2 E3TFA6 E3TFA6