View in Gene3D

CATH Superfamily 3.40.50.1820

Alpha/Beta hydrolase fold, catalytic domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 114886: Triacylglycerol lipase

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Triacylglycerol lipase. [EC: 3.1.1.3]
Triacylglycerol + H(2)O = diacylglycerol + a carboxylate.
  • The pancreatic enzyme acts only on an ester-water interface; the outer ester links are preferentially hydrolyzed.
 596 A0A023P672 A0A023P672 A0A023UG99 A0A023UG99 A0A068E839 A0A068E839 A0A069GAS4 A0A069GAS4 A0A075R371 A0A075R371
(586 more...)
Carboxylesterase. [EC: 3.1.1.1]
A carboxylic ester + H(2)O = an alcohol + a carboxylate.
  • Wide specificity; also hydrolyzes vitamin A esters.
  • The enzymes from microsomes also catalyze the reactions of EC 3.1.1.2, EC 3.1.1.5, EC 3.1.1.6, EC 3.1.1.23, EC 3.1.1.28, EC 3.1.2.2, EC 3.5.1.4, and EC 3.5.1.13.
  • Formerly EC 3.1.1.12.
 2 A0A1C8Y7C2 A0A1C8Y7C2
Phospholipase A(1). [EC: 3.1.1.32]
Phosphatidylcholine + H(2)O = 2-acylglycerophosphocholine + a carboxylate.
  • Has a much broader specificity than EC 3.1.1.4.
 2 P04635 P04635