The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 6091: Uridine phosphorylase 1, isoform CRA_a

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Uridine phosphorylase. [EC: 2.4.2.3]
Uridine + phosphate = uracil + alpha-D-ribose 1-phosphate.
  • The enzyme participates the the pathways of pyrimidine ribonucleosides degradation and salvage.
  • The mammalian enzyme also accepts 2'-deoxyuridine.
  • Formerly EC 2.4.2.23.
181 A0A060XU81 A0A061IGV0 A0A087QQ80 A0A087R0W3 A0A087VFW9 A0A087X7I0 A0A087XD27 A0A091CV58 A0A091DLM5 A0A091ET15
(171 more...)
Pyrimidine-nucleoside phosphorylase. [EC: 2.4.2.2]
(1) Uridine + phosphate = uracil + alpha-D-ribose 1-phosphate. (2) Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate. (3) 2'-deoxyuridine + phosphate = uracil + 2-deoxy-alpha-D-ribose 1-phosphate.
  • Unlike EC 2.4.2.3, and EC 2.4.2.4, this enzyme can accept both the ribonucleoside uridine and the 2'-deoxyribonucleosides 2'-deoxyuridine and thymidine.
  • The reaction is reversible, and the enzyme does not distinguish between alpha-D-ribose 1-phosphate and 2-deoxy-alpha-D-ribose 1-phosphate in the synthetic direction.
  • Formerly EC 2.4.2.23.
1 Q23588
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