The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Vaccinia Virus protein VP39
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 136484: Modification methylase AvaI

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Site-specific DNA-methyltransferase (cytosine-N(4)-specific). [EC: 2.1.1.113]
S-adenosyl-L-methionine + DNA cytosine = S-adenosyl-L-homocysteine + DNA N(4)-methylcytosine.
  • This is a large group of enzymes, the majority of which, with enzymes of similar site specificity listed as EC 3.1.21.3, EC 3.1.21.4 and EC 3.1.21.5, form so-called restriction-modification systems.
  • See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/
19 A0A073CWL0 A0A0A1VTN1 A0A0B7HWE7 A0A0S4KQB3 A0A1J1JEX9 A0A1J1KLF5 B0JY56 H1WIJ1 I4FNL1 I4G7G7
(9 more...)
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