The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Vaccinia Virus protein VP39
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 136295: Probable modification methylase HindII

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Site-specific DNA-methyltransferase (adenine-specific). [EC: 2.1.1.72]
S-adenosyl-L-methionine + adenine in DNA = S-adenosyl-L-homocysteine + N-6-methyladenine in DNA.
  • This is a large group of enzymes, most of which form so-called 'restriction-modification systems', with nucleases that possess similar site specificity (the nucleases are listed as either EC 3.1.21.3, EC 3.1.21.4 and EC 3.1.21.5).
  • See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/
52 A0A045IC62 A0A089QQU6 A0A0B7J8I9 A0A0D5QHH0 A0A0E7WNS9 A0A0G4DZM6 A0A0H3LFD5 A0A0H3MEC3 A0A0H3P5W6 A0A0K2I0R8
(42 more...)
TRNA(1)(Val) (adenine(37)-N(6))-methyltransferase. [EC: 2.1.1.223]
S-adenosyl-L-methionine + adenine(37) in tRNA(1)(Val) = S-adenosyl-L- homocysteine + N(6)-methyladenine(37) in tRNA(1)(Val).
  • The enzyme specifically methylates adenine(37) in tRNA(1)(Val) (anticodon cmo(5)UAC).
1 A0A0N7HJU9
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