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CATH Superfamily 3.40.50.150

Vaccinia Virus protein VP39

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Vaccinia Virus protein VP39
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 136209: 23S rRNA (Uracil-5-)-methyltransferase RumA

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
23S rRNA (uracil(747)-C(5))-methyltransferase. [EC: 2.1.1.189]
S-adenosyl-L-methionine + uracil(747) in 23S rRNA = S-adenosyl-L- homocysteine + 5-methyluracil(747) in 23S rRNA.
  • The enzyme specifically methylates uracil(747) at C(5) in 23S rRNA.
 137 A0A090I1Z6 A0A0C7RAK5 A0A0F0CAC0 A0A0H2YV01 A0A0L6ZDZ0 A0A0N8NT10 A0A0Q1GQH4 A0A0R3K002 A0A0U5NV53 A0A0U5NWM6
(127 more...)
TRNA (uracil(54)-C(5))-methyltransferase. [EC: 2.1.1.35]
S-adenosyl-L-methionine + uracil(54) in tRNA = S-adenosyl-L-homocysteine + 5-methyluracil(54) in tRNA.
  • Unlike this enzyme, EC 2.1.1.74 uses 5,10-methylenetetrahydrofolate and FADH(2) to supply the atoms for methylation of U54.
 17 A0A069A2L8 A0A097ASN5 A0A0M1UZM7 B0K851 D3T3P5 D4JJA9 D8GPN4 E8UWN4 F1ZXY8 G4D246
(7 more...)
23S rRNA (uracil(1939)-C(5))-methyltransferase. [EC: 2.1.1.190]
S-adenosyl-L-methionine + uracil(1939) in 23S rRNA = S-adenosyl-L- homocysteine + 5-methyluracil(1939) in 23S rRNA.
  • The enzyme specifically methylates uracil(1939) at C(5) in 23S rRNA.
  • The enzyme contains an [4Fe-4S] cluster coordinated by four conserved cysteine residues.
 11 A0A0F0CAC0 A0A0L6ZDZ0 A0A0N8NT10 A0A110A6Y0 A0A136WEQ4 A0A151ALW6 A0A151B3D5 A0A162UI42 A0A1A6B0A0 A0A1E7RYP8
(1 more...)
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