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CATH Superfamily 3.40.50.150

Vaccinia Virus protein VP39

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Vaccinia Virus protein VP39
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 136201: mRNA cap guanine-N7 methyltransferase

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
MRNA (guanine-N(7)-)-methyltransferase. [EC: 2.1.1.56]
S-adenosyl-L-methionine + G(5')pppR-RNA = S-adenosyl-L-homocysteine + m(7)G(5')pppR-RNA.
  • Adds an N(7)-methylguanine cap to mRNA.
  • The nucleoside next to the terminal guanosine may be either guanosine or adenosine.
 996 A0A016SK24 A0A016SK24 A0A022R023 A0A022R023 A0A023FX17 A0A023FX17 A0A026X3T5 A0A026X3T5 A0A044UPV7 A0A044UPV7
(986 more...)
MRNA guanylyltransferase. [EC: 2.7.7.50]
GTP + (5')pp-Pur-mRNA = diphosphate + G(5')ppp-Pur-mRNA.
  • Can modify also synthetic poly(A) and poly(G) to form the structures m(7)G(5')pppAn and m(7)G(5')pppGn.
 32 A0A0K1LDX7 A0A0K1LDX7 A4GDG1 A4GDG1 G0XXR0 G0XXR0 H2DTP7 H2DTP7 O57209 O57209
(22 more...)
Polynucleotide 5'-phosphatase. [EC: 3.1.3.33]
A 5'-phosphopolynucleotide + H(2)O = a polynucleotide + phosphate.
  • Does not act on nucleoside monophosphates.
  • Induced in Escherichia coli by T-even phages.
 30 A0A0K1LDX7 A0A0K1LDX7 G0XXR0 G0XXR0 H2DTP7 H2DTP7 O57209 O57209 P04298 P04298
(20 more...)