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CATH Superfamily 3.40.50.150

Vaccinia Virus protein VP39

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Vaccinia Virus protein VP39
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 136151: Macrocin-O-methyltransferase family protein

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Macrocin O-methyltransferase. [EC: 2.1.1.101]
S-adenosyl-L-methionine + macrocin = S-adenosyl-L-homocysteine + tylosin.
  • The 3-hydroxyl group of a 2-O-methyl-6-deoxy-D-allose residue in the macrolide antibiotic macrocin acts as methyl acceptor.
  • Isolated from Streptomyces fradiae.
  • Tylosin is a macrolide antibiotic.
  • Not identical with EC 2.1.1.102.
 25 A0A0B5NSQ1 A0A0G8EDW4 A0A0K6L2N3 A0A0U0FE08 A0A1C4ANS3 A0A1C4B5J9 A0A1C4B734 A0A1C4BHM2 A0A1D3NUH8 A0A1D3RDS5
(15 more...)
Mycinamicin III 3''-O-methyltransferase. [EC: 2.1.1.237]
S-adenosyl-L-methionine + mycinamicin III = S-adenosyl-L-homocysteine + mycinamicin IV.
  • The enzyme is involved in the biosynthesis of mycinamicin macrolide antibiotics.
 11 A0A0B5NSQ1 A0A0K6J351 A0A0K6L2N3 A0A0U0FE08 B7JEP9 C2TDC7 C3EYI2 C3FZU0 C3GFP4 C3HFE8
(1 more...)