The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Vaccinia Virus protein VP39
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 136149: Thiopurine S-methyltransferase, isoform CRA_d

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Thiopurine S-methyltransferase. [EC: 2.1.1.67]
S-adenosyl-L-methionine + a thiopurine = S-adenosyl-L-homocysteine + a thiopurine S-methylether.
  • Also acts, more slowly, on thiopyrimidines and aromatic thiols.
  • Not identical with EC 2.1.1.9.
2974 A0A009ZVV4 A0A009ZVV4 A0A010PDV0 A0A010PDV0 A0A010SNA9 A0A010SNA9 A0A017SV56 A0A017SV56 A0A023CAN5 A0A023CAN5
(2964 more...)
Thiocyanate methyltransferase. [EC: 2.1.1.n4]
S-adenosyl-L-methionine + thiocyanate = S-adenosyl-L-homocysteine + methyl thiocyanate.
    10 A0A078FY06 A0A078FY06 A0A078GFK8 A0A078GFK8 Q0WP12 Q0WP12 Q93V78 Q93V78 Q93XC4 Q93XC4
    Thiol S-methyltransferase. [EC: 2.1.1.9]
    S-adenosyl-L-methionine + a thiol = S-adenosyl-L-homocysteine + a thioether.
    • H(2)S and a variety of alkyl, aryl and heterocyclic thiols and hydroxy thiols can act as acceptors.
    8 A0A178VP97 A0A178VP97 A0A178VV10 A0A178VV10 O80562 O80562 Q6AWU6 Q6AWU6