The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Vaccinia Virus protein VP39
".
FunFam 135963: Protein N-lysine methyltransferase METTL21A
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 16 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein-lysine N-methyltransferase activity GO:0016279
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue in a protein substrate.
|
10 | A4FV42 (/ISS) A4FV98 (/ISS) A4IGU3 (/ISS) A6QP81 (/ISS) D3YWP0 (/ISS) Q5BLD8 (/ISS) Q5RE14 (/ISS) Q8BLU2 (/ISS) Q8C436 (/ISS) Q9CQL0 (/ISS) |
|
Protein-lysine N-methyltransferase activity GO:0016279
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue in a protein substrate.
|
4 | Q5VZV1 (/IDA) Q8WXB1 (/IDA) Q96AZ1 (/IDA) Q9H867 (/IDA) |
|
Protein-lysine N-methyltransferase activity GO:0016279
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue in a protein substrate.
|
4 | D3YWP0 (/ISO) Q8BLU2 (/ISO) Q8C436 (/ISO) Q9CQL0 (/ISO) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
3 | Q5VZV1 (/IPI) Q8WXB1 (/IPI) Q9H867 (/IPI) |
|
Methyltransferase activity GO:0008168
Catalysis of the transfer of a methyl group to an acceptor molecule.
|
2 | A4FV98 (/ISS) D3YWP0 (/ISS) |
|
Protein-lysine N-methyltransferase activity GO:0016279
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue in a protein substrate.
|
2 | Q8WXB1 (/TAS) Q9H867 (/TAS) |
|
Methyltransferase activity GO:0008168
Catalysis of the transfer of a methyl group to an acceptor molecule.
|
1 | Q96AZ1 (/IDA) |
|
Methyltransferase activity GO:0008168
Catalysis of the transfer of a methyl group to an acceptor molecule.
|
1 | D3YWP0 (/IMP) |
|
Methyltransferase activity GO:0008168
Catalysis of the transfer of a methyl group to an acceptor molecule.
|
1 | D3YWP0 (/ISO) |
|
S-adenosylmethionine-dependent methyltransferase activity GO:0008757
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.
|
1 | O13926 (/ISM) |
|
S-adenosylmethionine-dependent methyltransferase activity GO:0008757
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.
|
1 | P53970 (/ISS) |
|
Protein-lysine N-methyltransferase activity GO:0016279
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue in a protein substrate.
|
1 | D3YWP0 (/IMP) |
|
Hsp70 protein binding GO:0030544
Interacting selectively and non-covalently with Hsp70 proteins, any of a group of heat shock proteins around 70kDa in size.
|
1 | Q8WXB1 (/IPI) |
|
Hsp70 protein binding GO:0030544
Interacting selectively and non-covalently with Hsp70 proteins, any of a group of heat shock proteins around 70kDa in size.
|
1 | Q9CQL0 (/ISO) |
|
ATPase binding GO:0051117
Interacting selectively and non-covalently with an ATPase, any enzyme that catalyzes the hydrolysis of ATP.
|
1 | Q8WXB1 (/IPI) |
|
ATPase binding GO:0051117
Interacting selectively and non-covalently with an ATPase, any enzyme that catalyzes the hydrolysis of ATP.
|
1 | Q9CQL0 (/ISO) |
There are 11 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein methylation GO:0006479
The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom.
|
7 | A4FV42 (/ISS) A4IGU3 (/ISS) A6QP81 (/ISS) Q5BLD8 (/ISS) Q5RE14 (/ISS) Q8BLU2 (/ISS) Q9CQL0 (/ISS) |
|
Protein methylation GO:0006479
The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom.
|
2 | Q5VZV1 (/IDA) Q8WXB1 (/IDA) |
|
Protein methylation GO:0006479
The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom.
|
2 | Q8BLU2 (/ISO) Q9CQL0 (/ISO) |
|
Protein methylation GO:0006479
The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom.
|
2 | Q8WXB1 (/TAS) Q9H867 (/TAS) |
|
Peptidyl-lysine methylation GO:0018022
The methylation of peptidyl-lysine to form either the mono-, di- or trimethylated derivative.
|
2 | Q8WXB1 (/IDA) Q96AZ1 (/IDA) |
|
Peptidyl-lysine methylation GO:0018022
The methylation of peptidyl-lysine to form either the mono-, di- or trimethylated derivative.
|
2 | D3YWP0 (/ISO) Q9CQL0 (/ISO) |
|
Peptidyl-lysine methylation GO:0018022
The methylation of peptidyl-lysine to form either the mono-, di- or trimethylated derivative.
|
2 | A4FV98 (/ISS) D3YWP0 (/ISS) |
|
Peptidyl-lysine methylation GO:0018022
The methylation of peptidyl-lysine to form either the mono-, di- or trimethylated derivative.
|
1 | D3YWP0 (/IMP) |
|
Peptidyl-lysine trimethylation GO:0018023
The methylation of peptidyl-lysine to form peptidyl-N6,N6,N6-trimethyl-L-lysine.
|
1 | Q9H867 (/IDA) |
|
Peptidyl-lysine trimethylation GO:0018023
The methylation of peptidyl-lysine to form peptidyl-N6,N6,N6-trimethyl-L-lysine.
|
1 | Q8C436 (/ISO) |
|
Peptidyl-lysine trimethylation GO:0018023
The methylation of peptidyl-lysine to form peptidyl-N6,N6,N6-trimethyl-L-lysine.
|
1 | Q8C436 (/ISS) |
There are 12 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | A4FV98 (/ISS) D3YWP0 (/ISS) |
|
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
|
2 | A4FV98 (/ISS) D3YWP0 (/ISS) |
|
Intracellular GO:0005622
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
|
1 | Q96AZ1 (/IDA) |
|
Intracellular GO:0005622
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
|
1 | D3YWP0 (/ISO) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | O13926 (/IDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q8WXB1 (/TAS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q96AZ1 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | D3YWP0 (/ISO) |
|
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
|
1 | Q96AZ1 (/IDA) |
|
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
|
1 | D3YWP0 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | O13926 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q9H867 (/TAS) |
