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CATH Superfamily 3.40.50.150

Vaccinia Virus protein VP39

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Vaccinia Virus protein VP39
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 135933: Ribosomal RNA small subunit methyltransferase D

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
16S rRNA (guanine(966)-N(2))-methyltransferase. [EC: 2.1.1.171]
S-adenosyl-L-methionine + guanine(966) in 16S rRNA = S-adenosyl-L- homocysteine + N(2)-methylguanine(966) in 16S rRNA.
  • The enzyme efficiently methylates guanine(966) of the assembled 30S subunits in vitro.
  • Protein-free 16S rRNA is not a substrate for RsmD.
  • The enzyme specifically methylates guanine(966) at N(2) in 16S rRNA.
  • Formerly EC 2.1.1.52.
 31 A0A067AD81 A0A0A0TIV2 A0A0B0QBJ0 A0A0B7J0X7 A0A0K0HYM7 A0A0K6JXL3 A0A0K6K0E9 A0A0K6KB65 A0A0K6KJF2 A0A0K6KWM9
(21 more...)
MRNA (2'-O-methyladenosine-N(6)-)-methyltransferase. [EC: 2.1.1.62]
S-adenosyl-L-methionine + m(7)G(5')pppAm = S-adenosyl-L-homocysteine + m(7)G(5')pppm(6)Am.
  • mRNA containing an N(6),2'-O-dimethyladenosine cap.
 2 A0A060S374 C0H5I0
Site-specific DNA-methyltransferase (adenine-specific). [EC: 2.1.1.72]
S-adenosyl-L-methionine + adenine in DNA = S-adenosyl-L-homocysteine + N-6-methyladenine in DNA.
  • This is a large group of enzymes, most of which form so-called 'restriction-modification systems', with nucleases that possess similar site specificity (the nucleases are listed as either EC 3.1.21.3, EC 3.1.21.4 and EC 3.1.21.5).
  • See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/
 2 A0A0E1LP93 I2C4S5